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Found 579 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 60 years
Accepts healthy volunteer
All genders
This study seeks to understand why some people who got COVID-19 are still sick many months after being infected, and how this affects the body. Being sick for a long time is sometimes called “Long COVID” or “PASC”, which stands for post-acute sequelae of SARS-CoV-2 infection. Through this study, we …
 Phase I Clinical Trial of Adoptive Transfer of Autologous Folate Receptor alpha Redirected T Cells for Recurrent High Grade Serous Ovarian  Fallopian Tube  or Primary Peritoneal Cancer
99 years or below
All genders
Phase 1
This is a Phase I study evaluating the safety and feasibility of intraperitoneal administered lentiviral transduced MOv19-BBz CAR-T cells in 4 cohorts with or without cyclophosphamide + fludarabine in a 3+3 dose escalation design. Up to 18 evaluable subjects will be treated.
 Phase 3  open label  single arm study to evaluate efficacy and safety of FIX gene transfer with PF-06838435 (rAAV Spark100-hFIX-Padua) in adult male participants with moderately severe to severe hemophilia B (FIX:C= or -2%) (BeneGene-2)
99 years or below
All genders
Phase 3
The research study is being conducted to test the safety and effectiveness of the study drug which is a gene therapy based treatment. Researchers want to see if the drug works to prevent the bleeding episodes commonly experienced by patient with Hemophilia B and to advance science and medicine. Subjects …
 A Randomized study of EHR Defaults and Using social Comparison feedback to Effectively decrease opioid prescription pill burden - The REDUCE Trial
99 years or below
All genders
Observational
Opioid-related abuse and overdose represent a growing national epidemic in the United States. Clinician practice patterns play an important role: opioid prescriptions impact the likelihood that patients will misuse or become dependent on these medications, with longer prescriptions leading to greater sustained use. In this study, we will evaluate a …
99 years or below
All genders
Phase 1
The purposes of this study are to see if the study drugs, venetoclax and gilteritinib can be safely and effectively combined for the treatment of patients with acute myeloid leukemia (AML) that has returned after prior treatment, or has failed to respond to prior treatment and identify potential biomarkers.
99 years or below
All genders
The purpose of this study is to see if niraparib added to a standard treatment (abiraterone acetate and prednisone) will work better than abiraterone acetate and prednisone alone in treating men with metastatic prostate cancer with specific genetic changes. Eligible subjects will be men with metastatic prostate cancer.
 Multimodal Evaluation of Spaceflight Participants Health Space Adventures 1 (MESH SPA-1)
18 years - 99 years
All genders
Observational
One commercial astronaut spending 2 weeks on the international space station will be participate in pre- and post-flight research by several investigators. The team at the University of Pennsylvania investigates cognitive performance, alertness and mood as well as changes in activity, heart rate and blood oxygen concentration as measured with …
 A  Study of Osimertinib with or without Platinum Plus Pemetrexed Chemotherapy  as First-line Treatment in Patients with Epidermal Growth Factor Receptor (EGFR) Mutation- Positive  Locally Advanced or Metastatic Non-small Cell Lung Cancer
18 years - 99 years
All genders
Phase 3
Interventional
The purpose of this study is to try to find out if an experimental combination of an oral medication called osimertinib when used in combination with chemotherapy is more effective than giving osimertinib alone for the treatment of non-small cell lung cancer (NSCLC). Eligible subjects will be adult subjects with …
 A Umbrella Study with Rolling Arms of Investigational Agents with Pembrolizumab in Combination with Chemotherapy in Treatment-Naive Patients with Advanced Non-small Cell Lung Cancer (NSCLC)
18 years - 99 years
All genders
Phase 2
This is a substudy of an umbrella study (MK-3475-U1). Subjects will be enrolled to the screening protocol and then subsequently enrolled to one of the substudies. This substudy examines investigational agents (MK-7684, MK-5890, MK-4830) in combination with pembrolizumab plus standard chemotherapy in treatment-naïve participants with advanced NSCLC.
 Safety and Immunogenicity Study of SARS-CoV-2 mRNA-1273 Vaccine in Adult Solid Organ Transplant Recipients and Healthy Controls
18 years - 99 years
Accepts healthy volunteer
All genders
Phase 3
The research study is being conducted to study the effectiveness of the mRNA-1273 study vaccine in people who have received a kidney or liver transplant. Healthy participants are being included in the study to compare the results from these participants to those who have had a kidney or liver transplant. …
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