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Found 579 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years or below
Female
Interventional
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery. Eligible participants will be women ages 18+ scheduled for vaginal birth.
 A Study of Venetoclax (ABT-199) in Combination with Liposomal Vincristine in Patients with Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia
18 years - 99 years
All genders
Phase 1
Interventional
This study is being done to determine what effects the therapy venetoclax has on acute lymphoblastic leukemia (ALL).This investigational therapy will be added to what is a standard, liposomal vincristine, to treat relapsed ALL.
 Brain Arterio-Venous Metabolomic Profiling
18 years - 99 years
All genders
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
 Functional Lung Avoidance Radiation Therapy Using Hyperpolarized Xenon-129 MRI
18 years - 99 years
All genders
Phase 1
The primary outcomes will be to establish the safety and feasibility of inhaled imaging in patients with NSCLCand to develop a robust RT planning protocol incorporating both standard of care metrics and those derived from inhaled imaging
18 years - 99 years
All genders
Interventional
This research study is being done to investigate if a new technique called ‘needle-based confocal laser endomicroscopy’ (abbreviated as nCLE) is helpful in patients who are undergoing a bronchoscopy to obtain a tissue sample (biopsy) of a lung nodule. The nCLE technique will be used as an addition to the …
 An Open-label Phase 1/1b Study to Evaluate the Safety and Pharmacokinetics of JNJ-73841937 (Lazertinib)  a Third Generation EGFR-TKI  as Monotherapy or in Combinations With JNJ-61186372  a Human Bispecific EGFR and cMet Antibody in Participants With Advanced Non-Small Cell Lung Cancer
18 years - 99 years
All genders
Phase 1
the purpose of this study is to see if lazertinib and JNJ-61186372 are safe and useful for treating patients with a type of lung cancer called advanced non-small cell lung cancer (NSCLC). Eligible subjects will be those with NSCLC.
18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this study are to determine the maximum dose of FF-10832 that can be tolerated when taken in combination with pembrolizumab and to determine whether FF10832 taken by itself or in combination with pembrolizumab has anti-tumor activity.
 Testing of Magnetic Resonance Methods at 7.0 Tesla
18 years - 60 years
All genders
Observational
The research study will test the performance of new magnetic resonance imaging and spectroscopy techniques at 7.0 Tesla. These new methods have already been tested in model systems and need to be tried on human subjects prior to use in patient population.
 Cystic Fibrosis Microbiome
18 years - 99 years
All genders
Among lung transplant recipients who survive to 5 years, half suffer from chronic lung allograft dysfunction (CLAD). This study will evaluate how changes in the lung microbiome may cause CLAD in Cystic Fibrosis patients who have been transplanted. This is a case-control study of Cystic Fibrosis lung transplant recipients to …
 ASPEN- A Phase 3  Randomized  Double-Blind  Placebo-Controlled Study to Assess the Efficacy  Safety  and Tolerability of Brensocatib Administered Once Daily for 52 Weeks in Subjects With Non-Cystic Fibrosis Bronchiectasis
18 years - 85 years
All genders
Phase 3
Interventional
Penn Medicine patients already participating in protocol INS1007 301 will be invited to participate in this study. The Pharmacokinetic (PK) portion of this substudy is designed to evaluate the amount of brensocatib present in your blood at certain time periods before and after the study drug is administered, and the …
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