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Found 582 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Long-Term Safety Extension Study of Mavacamten (MYK-461) in Adults with Hypertrophic Cardiomyopathy Who Have Completed the MAVERICK-HCM (MYK-461-006) or EXPLORER-HCM (MYK-461-005) Trials (MAVA-LTE)

All genders
This is a multicenter study to evaluate the long-term safety and tolerability of mavacamten in participants with nHCM who completed MAVERICK-HCM through Week 24 and enroll into this study within 3 months. All participants will receive active study drug as described below, but their status (active or placebo) in the …
 The Association Between CBT-I Dose and Innate Immunity in Insomnia and Fatigue in Prostate Cancer Patients

The Association Between CBT-I Dose and Innate Immunity in Insomnia and Fatigue in Prostate Cancer Patients

18 years - 99 years
All genders
The research study is being conducted secondary and after your completion of the primary study (Effect of Radiation Therapy on Sleepiness and Activity in Prostate and Breast Cancer Patients). The purpose of the current study is to assess the effectiveness of a behavioral treatment for insomnia (also known as Cognitive …
 Cerebrovascular reactivity assessed with functional near-infrared spectroscopy as a biomarker of traumatic microvascular injury after traumatic brain injury

Cerebrovascular reactivity assessed with functional near-infrared spectroscopy as a biomarker of traumatic microvascular injury after traumatic brain injury

All genders
Traumatic cerebrovascular injury (TCVI) is common after traumatic brain injury (TBI) and an attractive target for therapeutic intervention. We will longitudinally measure cerebrovascular reactivity (CVR) by functional near-infrared spectroscopy (fNIRS) in acute (3 days from injury), subacute, and chronic phases after TBI as a biomarker of TCVI as compared to …
 HOPE Trial

HOPE Trial

18 years - 99 years
All genders
HOPE is a randomized clinical trial that will evaluate approaches to reducing pain and opioid use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage renal disease. The hypothesis is that pain coping skills training will be effective at reducing pain and opioid use, and that buprenorphine …
 KEYMAKER-U02

KEYMAKER-U02

18 years - 99 years
All genders
Phase 1
Interventional
Patients will be recruited from within the Penn Medicine Abramson Cancer Center pool of patients. This sub-study is part of a larger research study that is testing experimental treatments for melanoma. This sub-study is testing experimental drugs when they are given before and/or after melanoma surgery. Subjects will be assigned …
 DEFENDO- Study to evaluate safety and efficacy of ophthalmic solution (Oxervate) in patients with Stage 1 Neurotrophic Keratitis (NK)

DEFENDO- Study to evaluate safety and efficacy of ophthalmic solution (Oxervate) in patients with Stage 1 Neurotrophic Keratitis (NK)

All genders
This clinical study will be a multi-center, open label, prospective study of 8 weeks of treatment with 24 weeks of follow-up to evaluate the safety and efficacy of OXERVATE 0.002% (20 mcg/mL) cenegermin-bkbj ophthalmic solution administered as one drop in the affected eye(s), 6 times per day at 2-hour intervals, …

Study to evaluate 6-week treatment cycles of rozanolixizumab in study participants with gMG.

18 years - 99 years
All genders
Phase 3
Interventional
The research study is being conducted to test the long-term safety, tolerability and effectiveness of rozanolixizumab in adult patients with generalized myasthenia gravis (MG) who have already taken part in the MG0003 study and is intended to replace MG0004. This study will evaluate 6-week treatment cycles of rozanolixizumab in study …
 Defining the role of germline genetic variants in gastric cancer tumorigenesis

Defining the role of germline genetic variants in gastric cancer tumorigenesis

All genders
The research study is being conducted to better understand factors that lead to gastric (stomach) cancer, including differences in our genes that may put some people at increased risk of developing gastric cancer compared to other people. Both people with increased risk as well as people with average risk of …
 Circulating Biomarkers for Glioma

Circulating Biomarkers for Glioma

18 years - 99 years
All genders
Subjects will be recruited from the Radiation Oncology and Neurosurgery practices at the Hospital of the University of Pennsylvania. The treating radiation oncologist will determine if the patient is a potential research candidate and has the capacity to consent. The goal of this study is to collect and analyze blood …

Understanding the long-term impact of COVID on children and families

Accepts healthy volunteer
All genders
Observational
Purpose of this study is to understand why some people who got COVID-19 are still sick many months after being infected, and how this affects the body. This is sometimes called “Long COVID” or “PASC”, which stands for post-acute sequelae of SARS-CoV-2 infection. Children who have and have not had …
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