Found 582 Barrett's Esophagus trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Umbrella Study with Rolling Arms of Investigational Agents with Pembrolizumab in Combination with Chemotherapy in Treatment-Naive Patients with Advanced Non-small Cell Lung Cancer (NSCLC)
This is a substudy of an umbrella study (MK-3475-U1). Subjects will be enrolled to the screening protocol and then subsequently enrolled to one of the substudies. This substudy examines investigational agents (MK-7684, MK-5890, MK-4830) in combination with pembrolizumab plus standard chemotherapy in treatment-naïve participants with advanced NSCLC.
Safety and Immunogenicity Study of SARS-CoV-2 mRNA-1273 Vaccine in Adult Solid Organ Transplant Recipients and Healthy Controls
The research study is being conducted to study the effectiveness of the mRNA-1273 study vaccine in people who have received a kidney or liver transplant. Healthy participants are being included in the study to compare the results from these participants to those who have had a kidney or liver transplant. …
A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum
The purpose of this study is to compare the effectiveness and implementation of two suicide prevention strategies for autistic youth: the Safety Planning Intervention tailored for Autistic individuals (SPI-A) and SPI-A plus follow-up care (SPI-A+). Participants are 150 clinicians and 1500 autistic youth (ages 15-24) who receive either SPI-A or …
Chemotherapy Induced Peripheral Neuropathy Natural History Study (EPIPHANY)
This is a prospective natural history study of CIPN in approximately 200 participants receiving taxanes (paclitaxel, docetaxel) for breast cancer or vincristine for lymphoma. Participants will be enrolled over approximately 1-year.The purpose of this present study is to prospectively collect clinical and biomarker data from patients receiving neurotoxic chemotherapy who …
A Study with Rolling Arms of Investigational Agents in Combination with Pembrolizumab in Patients with Advanced Non-small Cell Lung Cancer (NSCLC)
This is a substudy of an umbrella study (MK-3475-U1). Subjects will be enrolled to the screening protocol and then subsequently enrolled to one of the substudies. This substudy examines investigational agents (MK-0482, MK-5890, MK-4830) in combination with pembrolizumab based therapy in patients with PD-(L)1 refractory NSCLC in a rolling-arm design
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib versus Placebo Following Adjuvant Chemotherapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1 BRCA2 or PALB2 Mutation
The purpose of this study is to compare the usual treatment alone to using one year of olaparib. We will enroll subject who have been diagnosed with pancreatic cancer and have undergone surgery to remove the cancer. Only patients who are found to have a BRCA1, BRCA2 or PALB2 mutation …
Innovative Combination Immunotherapy for Metastatic Triple Negative Breast Cancer (TNBC)
This phase II trial studies how well avelumab in combination with binimetinib, utomilumab, or anti-OX40 antibody PF-04518600 works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like …
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation after CABG
The purpose of the research is to compare two commonly used treatment strategies for managing atrial fibrillation after cardiac surgery. Patients 18 yrs. or older are randomized within 7 days after scheduled to undergo coronary artery bypass grafting (CABG), also known as bypass surgery. Only patients that undergo isolated CABG …
SMaRT Blood: Single-unit versus Multiple-unit pRBC Transfusion in non-acute postpartum anemia
Blood transfusion is often recommended for women who have anemia (low blood counts) after delivering a baby. Currently, many doctors give 2 units, or packets, of blood because they expect that everyone will need 2. However, it may be better to only give 1 unit at a time to raise …
The Impact of COVID 19 on Laryngeal Function Voice Communication and Quality of Life
This project aims to create a national cohort of COVID-19 ICU survivors, quantify the longer-term burden of COVID-19 infection and treatment on laryngeal function, voice, communication and quality of life within the cohort and identify potential intervention targets to prevent post-intubation laryngeal injuries. Subjects will be recruited from Penn's Otorhinolaryngology …
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