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Found 582 Barrett's Esophagus trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The NICU Antibiotics and Outcomes Trial (NANO)
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life. In this 802-subject multicenter placebo-controlled randomized clinical trial, the hypothesis to be tested is that the incidence of adverse outcomes …
A Multiple-Site Phase 1/2 Safety and Efficacy Trial of AGTC 402 a Recombinant Adeno-associated Virus Vector Expressing CNGA3 in Patients with Congenital Achromatopsia Caused by Mutations in the CNGA3 Gene
Achromatopsia is an inherited retinal disorder characterized by markedly reduced visual acuity, nystagmus, photoaversion (intolerance to bright light), a small central scotoma, eccentric viewing, and complete or severe loss of color discrimination. The genetic mutations of the disease can be established in the majority of individuals. Approximately 25% are caused …
Bupivacaine RCT- Bupivacaine as Adjuvant for Post-operative Pain in Mohs micrographic surgery
The research study is being conducted to find the best ways to reduce pain after Mohs surgery. The research team hopes to learn if adding additional numbing medication at the end of surgery will help reduce pain afterwards. Penn Medicine patients having Mohs surgery will be invited to participate in …
A pilot randomized control trial to determine the feasibility of a hypnosis intervention for the treatment of bladder pain syndrome/interstitial cystitis.
The purpose of this research study is determine the feasibility of a hypnosis intervention to women with bladder pain syndrome. We also plan to assess the effect of hypnotic words and suggestions on brain function. Hypnotherapy has been studied in other chronic pain conditions and has been shown to be …
UPCC 44419: Randomized Trial of Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia (AML)
The purpose of this study is to compare the effectiveness of gilteritinib to midostaurin in patients receiving standard combination chemotherapy for FLT3 AML. Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 65 will be randomized to receive gilteritinib or midostaurin during induction and …
Cancer detection rate of Abbreviated (Fast) Breast MRI (AB-MR) after negative Digitial Breast Tomosynthesis in Women status post Conservation Therapy (BCT)
Women treated for primary breast cancer who undergo breast conservation therapy face an increased risk of developing a second breast cancer in the ipsilateral and the contralateral breast. Although mammographic screening is recommended annually, the sensitivity of mammography is limited in these patients due to the post treatment changes from …
PEERLESS Study
The FlowTriever Retrieval/Aspiration System (referred to as “FlowTriever”) is an FDA-cleared device designed to treat pulmonary embolism (PE). A PE is a blood clot trapped in your lung. The FlowTriever is used to remove the clot by pulling it into a catheter so that the clot can be removed from …
Observational Study of Outcomes after EchoMark and EchoSure-based Free Flap Monitoring
The purpose of this study is to evaluate the performance of the EchoMark and EchoSure (both FDA approved devices) as an ultrasound-based method of monitoring the viability of free flaps and patency of at-risk vessels. The implant and ultrasound will be used per IFU. The primary purpose of the study …
UPCC 37420 Phase 2 Study of Belantamab Mafodotin As Pre- and Post- Autologous Stem Cell Transplant Consolidation and Maintenance For Multiple Myeloma
The research study is being conducted to see if combining an investigational drug, called belantamab mafodotin, with standard-of-care autologous stem cell transplant and maintenance therapy in patients with myeloma can help reduce the amount of myeloma cells that can be detected in patients after transplant. We will also study if …
Vitamin D Receptor Agonist Paricalcitol Plus Gemcitabine and Nab-Paclitaxel in Patients with Metastatic Pancreatic Cancer
This research study consists of a safety run-in phase and a randomized phase 2 study which include subjects with previously-untreated, metastatic pancreatic adenocarcinoma. In the run-in safety study, the safety of adding two formulations (IV or Oral) of paricalcitol to a standard chemotherapy program of gemcitabine and nab-paclitaxel will be …
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