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Found 116 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 INSIGHT: Investigation of Clot in Ischemic Stroke and Hematoma Evacuation

INSIGHT: Investigation of Clot in Ischemic Stroke and Hematoma Evacuation

18 years - 99 years
All genders
Observational
The aim of the study is to collect and analyze specimen from ischemic stroke patients undergoing thrombectomy procedures and from patients undergoing minimally invasive surgery for intracranial hematoma evacuation. Clot and blood specimen will be analyzed via histology, RNA sequencing, Single Nucleotide Polymorphisms (SNPs), and proteomic analysis.
 Repeatability  Reproducibility  and Efficacy Testing of Automated Hemodynamic Output by Transthoracic Echocardiography

Repeatability Reproducibility and Efficacy Testing of Automated Hemodynamic Output by Transthoracic Echocardiography

18 years - 99 years
All genders
Observational
This study will involve scanning of a patient's chest wall with an approved ultrasound device (Lumify) to obtain images prior to a patient undergoing cardiac surgery. The investigational device involved in this study will be the software that automatically outputs heart data from those chest wall images (Automated Hemodynamics Application).
 Drug-Induced Sleep Endoscopy (DISE): Phenotyping Obstruction Patterns

Drug-Induced Sleep Endoscopy (DISE): Phenotyping Obstruction Patterns

18 years - 99 years
All genders
Interventional
The research study is being done to better understand how and why the airway collapses during sleep. We would like to find out what types of things (for example, air flow, air pressure, or face shape) affect if someone’s throat closes up during sleep and how well they do after …

Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection Of Lung Malignancies.

18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this research study is to learn if the investigational study drug, pegsitacianine, helps in seeing the primary lung cancer tumor and identifying any additional cancerous tissue present in the lung for removal at the time of standard of care cancer surgery. Each participant will receive a single …

Metabolomic Assessment of Frailty in Surgical Patients

All genders
PURPOSE: The overall objective of the project is to perform comparative metabolomics on frail and non-frail patients undergoing major surgery. We hypothesize that frail patients will have distinct baselines, suffer greater metabolic derangements, and recover more slowly than non-frail patients. Additionally, we hypothesize that those patients who undergo prehab will …
 Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)  A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers

Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers

All genders
Phase 3
The purpose of this study is to find if adding the study drug, nivolumab (also known as OPVIDO), will limit lung cancer from growing back in patients with early stage non-small cell lung cancer. Nivolumab is a drug that may turn on the body's immune system to attack any cancer …
 Breethe Abiomed Recovery Trial

Breethe Abiomed Recovery Trial

18 years - 99 years
All genders
Observational
The intent of the BART Study is to utilize observational data of the Abiomed Breethe OXY-1 System™ in real-world settings to drive best practice usage patterns identified through study analysis, to serve as a tool to measure and improve the quality of patient care and to serve as a resource …
 Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature (ELEGANCE)

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature (ELEGANCE)

18 years - 99 years
All genders
Observational
ELEGANCE is a global prospective, non-randomized, open-label, multi-center Registry to collect Real-World Data, including health economic data, to support the use of commercially available drug-eluting BSC devices for the treatment of lesions located in the peripheral vasculature

ABC 123 July

All genders
This post-market, prospective, interventional, global, multi-center, randomized, nonblinded, dual-arm, clinical trial study will generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft System versus Gore Excluder/Excluder Conformable AAA Endoprosthesis in subjects with Abdominal Aortic Aneurysm (AAA). The primary objective is to evaluate sac regression outcomes in …
 Evaluation of Corneal Confocal Microscopy in Ocular Surface Disease and/or Neuropathic Pain Patients

Evaluation of Corneal Confocal Microscopy in Ocular Surface Disease and/or Neuropathic Pain Patients

All genders
The purpose of this study is two-fold. Since there is currently no FDA approved software to analyze these images, the images taken will be used to help improve and refine current software, or help develop new software, in the hopes that it will be approved by the FDA. The images …
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