Search filters

Filters
Clear All

Phase

  • 10
  • 10
  • 18
  • 14
  • 1
  • 55
  • 116
  • 25
  • 1
  • 9
  • 106

Found 116 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 CentriMag Failure-to-Wean Post cardiopulmonary bypass
18 years - 99 years
All genders
Interventional
This study will gather real-world information on the post-market performance, and confirm safety and effectiveness of the CentriMag Circulatory Support System for patients surviving up 30 days post support or to hospital discharge, and for subjects who do not recover and are bridged to a heart transplant or long-term assist …
 Preliminary Evaluation of Septin9 in Familial Adenomatous Polyposis Patients
1 years - 99 years
All genders
The purpose of this research study is to collect blood samples and applicable medical history from subjects diagnosed with hereditary colon cancer syndromes like FAP, Lynch Syndrome and MYK-associated polyposis and their family members. These samples will be used to evaluate the ability of a blood test to provide early …
18 years - 99 years
Female
Interventional
The purpose of this study is to test a new scanner device that combines two types of imaging called Breast Positron Emission Tomography (BPET) and Digital Breast Tomosynthesis (DPT) for imaging of a radioactive imaging drug called 18F-Fluoroestradiol (FES), as a diagnostic device for imaging estrogen receptor (ER) positive breast …
18 years - 75 years
All genders
Phase 2
This is a multicenter, randomized, open-label study of Toca 511 and Toca FC versus standard of care (SOC) that comprises Investigators choice of either single agent chemotherapy (lomustine or temozolomide) or bevacizumab administered to subjects undergoing resection for first or second recurrence (including this recurrence) of glioblastoma or anaplastic astrocytoma. …
18 years or above
All genders
Observational
This study investigates the use of short femoral stems in hip arthroplasty for patients with primary hip osteoarthritis or osteonecrosis. The purpose of this study is to evaluate the outcomes when these stems are implanted through a minimally invasive anterior approach.The study focuses on understanding the safety and effectiveness of …
 Trial of ASP-1929 Photoimmunotherapy Versus Physician's Choice Standard of Care for the Treatment of Locoregional  Recurrent Head and Neck Squamous Cell Carcinoma
18 years - 99 years
All genders
Phase 3
This is a Phase 3, randomized, double-arm, open-label trial of ASP-1929 photoimmunotherapy (ASP-1929 PIT) versus physician's choice standard of care (SOC) for the treatment of locoregional, recurrent head and neck squamous cell carcinoma (HNSCC) in patients who have failed or progressed on or after at least two lines of therapy, …
99 years or below
All genders
Phase 2
Primary Objectives Cohort 1: To determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D) of ASP8374 when administered with cemiplimab among recurrent malignant glioma participants. Cohort 2: To determine if neoadjuvant immune checkpoint blockade (ICB) with ASP8374, cemiplimab and the combination of ASP8374 plus cemiplimab will induce …
 IMAGING OF IN VIVO SIGMA-2 RECEPTOR EXPRESSION WITH [18F]ISO-1 POSITRON EMISSION TOMOGRAPHY (PET/CT) IN METASTATIC BREAST CANCER
18 years - 80 years
Female
Patients with metastatic breast cancer, that is biopsy proven or clinically documented by standard imaging (e.g. CT, MRI, Bone Scan, Ultrasound, FDG PET/CT), may be eligible for this study.  Patients may participate in this study, if they are at least 18 years of age.  We anticipate enrolling up to 30 …
 AMC 083 / UPCC 12716: Tissue Acquisition for Analysis of Prognostic Factors  Immunology  and Genetic Progression of HIV-1 Associated Malignancies
18 years - 99 years
All genders
The main purpose of this study is to collect tissue from people diagnosed with HIV-associated cancer. We will use these samples to look for genetic changes associated with HIV- and other virus-related cancers. This may lead to better ways of preventing, detecting, and treating HIV-associated cancers.
18 years - 99 years
All genders
Phase 1
Interventional
The research study is being conducted to determine if a same-day intravenous (into a vein) injection of indocyanine green (ICG) detected using an imaging system, can be a useful tool in identifying and differentiating tumor tissue from normal tissues.
61 - 70 of 116