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Found 112 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 99 years
All genders
Phase 2
Interventional
The main purpose of this research study is to determine the likelihood of cancer growing back in the throat or in the neck, 2 years after completion of radiation, if lower doses of radiation are used to a smaller area of the head and neck region, than is currently the …
 SIMCAP (Surgery in Metastatic Carcinoma of Prostate): Phase 2.5 multi-institution randomized prospective clinical trial evaluating the impact of cytoreductive radical prostatectomy combined with best systemic therapy on oncologic and quality of life outcomes in men with newly diagnosed metastatic prostate cancer
18 years - 100 years
All genders
Phase 2
This study investigates the effects of adding cytoreductive radical prostatectomy (CRP) to the standard treatment, best systemic therapy (BST), for metastatic prostate cancer (mPCa). CRP removes as much of the cancer as possible (and radical prostatectomy removes only prostate) while BST uses drugs toxic to cancer cells: chemotherapy and androgen …
 TRILOGY
18 years - 65 years
All genders
The target population are patients at Penn Medicine undergoing elective bariatric surgery; and are additionally participating in POW-R study ( Protocol #843280) Patients will be recruited to undergo liver wedge and visceral adipose tissue biopsy and provide blood samples. Liver samples will be processed for RNA, metabolomics, and biochemical and …
 A study assessing the efficacy and feasibility of virtual cardiac rehabilitation with remotely monitored exercise (VCR)
18 years - 99 years
All genders
This will be an observational study to investigate the feasibility and efficacy of a home-based, tech enabled, remotely supervised, cardiac rehabilitation (CR) program in qualifying American adults who cannot participate in traditional center based rehab.This study aims to investigate the feasibility and effectiveness of Carda Healths remotely administered cardiac rehab …
 JAGUAR- ObJective Analysis to GaUge EVAR Outcomes Through Randomization
21 years - 99 years
All genders
Phase 4
This post-approval study will collect safety, performance, effectiveness, and neck dilatation data on Alto Abdominal Stent Graft System for the endovascular treatment of infrarenal abdominal aortic aneurysms and evaluate real-world outcomes in comparison to commercially available comparator devices. Penn Medicine patients with the Alto Abdominal Stent Graft System, a device …
 Intramolecular Imaging with ICG (PRIME)
18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this protocol is to monitor the rate of recurrence in patients who undergo cancer surgery. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove …
 TAMBE- Evaluation of the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
18 years - 99 years
All genders
Normal 0 false false false EN-US JA X-NONE Patients with thoracoabdominal or pararenal aneurysm disease will be asked to take part in this research study This research study will look at treating thoracoabdominal or pararenal aneurysm disease with a new stent-graft design. The reason we are doing this research study …
 Prospective Open-Label Study Of Andexanet Alfa In Patients
18 years - 85 years
All genders
Phase 2
Andexanet, a rationally designed, recombinant analog of endogenous human FXa, has been developed to rapidly and potently reverse FXa inhibition and restore physiologic coagulation. This study will examine the use of Andexanet inIn patients requiring urgent surgery who are being treated with a direct or indirect FXa inhibitor,
 Validation of the prospective registry of outcomes in patients electing lung transplantation (PROPEL)
18 years - 99 years
All genders
The research study is being conducted to develop a test to predict a common complication after lung transplant called primary graft dysfunction (PGD). Predicting PGD before using donor organs may help reduce deaths and improve outcomes of patients receiving a lung transplant in the future.
 Surgical Therapy for Obstructive Sleep Apnea on Blood Pressure & Peripheral Arterial Tonometry
18 years - 90 years
All genders
The research study is being done to look at the effect of sleep apnea surgery on different measures ofcardiovascular (heart) function in people with obstructive sleep apnea.
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