Found 116 surgery trials
A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Purpose is to determine if cemiplimab (given as infusion in the vein) will prevent cutaneous squamous cell cancer from returning after surgery and radiation. Subjects at least 18 years of age who have had surgery and radiation therapy for cutaneous squamous cell cancer, and there is a risk that this …
The research study is being conducted to test the study drug PB2452 to see if it is safe and will reverse the bleeding effects of Brilinta® (also known as ticagrelor). Candidates must be taking Brilinta® (ticagrelor) or show intake within the past 3 days. They will be considered for participation …
The target population are patients at Penn Medicine undergoing elective bariatric surgery; and are additionally participating in POW-R study ( Protocol #843280) Patients will be recruited to undergo liver wedge and visceral adipose tissue biopsy and provide blood samples. Liver samples will be processed for RNA, metabolomics, and biochemical and …
This will be an observational study to investigate the feasibility and efficacy of a home-based, tech enabled, remotely supervised, cardiac rehabilitation (CR) program in qualifying American adults who cannot participate in traditional center based rehab.This study aims to investigate the feasibility and effectiveness of Carda Healths remotely administered cardiac rehab …
This post-approval study will collect safety, performance, effectiveness, and neck dilatation data on Alto Abdominal Stent Graft System for the endovascular treatment of infrarenal abdominal aortic aneurysms and evaluate real-world outcomes in comparison to commercially available comparator devices. Penn Medicine patients with the Alto Abdominal Stent Graft System, a device …
Patients will be recruited from within the Penn Medicine Abramson Cancer Center pool of patients. This sub-study is part of a larger research study that is testing experimental treatments for melanoma. This sub-study is testing experimental drugs when they are given before and/or after melanoma surgery. Subjects will be assigned …
The purpose of this protocol is to monitor the rate of recurrence in patients who undergo cancer surgery. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove …
Andexanet, a rationally designed, recombinant analog of endogenous human FXa, has been developed to rapidly and potently reverse FXa inhibition and restore physiologic coagulation. This study will examine the use of Andexanet inIn patients requiring urgent surgery who are being treated with a direct or indirect FXa inhibitor,
The research study is being conducted to develop a test to predict a common complication after lung transplant called primary graft dysfunction (PGD). Predicting PGD before using donor organs may help reduce deaths and improve outcomes of patients receiving a lung transplant in the future.
This phase II/III trial compares the effect of adding chemotherapy before and after surgery versus after surgery alone (usual treatment) in treating patients with stage II-III gallbladder cancer. This study will determine whether giving chemotherapy before surgery increases the length of time before the cancer may return and whether it …
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