Found 116 surgery trials
A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This phase II trial studies how well avelumab in combination with binimetinib, utomilumab, or anti-OX40 antibody PF-04518600 works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like …
This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. This trial is open to Penn Medicine's Abramson Cancer Center patients only. Please contact the …
Patients greater than 18 years of age undergoing a neurosurgical procedure at Penn Medicine will be approached for enrollment. Currently, this study is open only at the HUP and Penn Presbyterian Medical Center locations.Current research suggests that severe bodily stress caused by surgery may impair the immune system's ability to …
The goal of this study is to improve the reliability of acquiring open-set speech recognition following ABI placement for retrocochlear deafness, to evaluate whether state of consciousness influences speech-based ABR. The researchers hypothesize that: 1) It will be possible to elicit speech-based ABR from surgically anesthetized patients. 2) Surgically anesthetized …
The purpose of this research study is to learn more about how the brain stores and retrieves different kinds of information from memory, and whether brain stimulation can improve the storage and retrieval of memories. We are enrolling subjects with drug-resistant epilepsy, who are expected to undergo placement of electrodes …
This project aims to create a national cohort of COVID-19 ICU survivors, quantify the longer-term burden of COVID-19 infection and treatment on laryngeal function, voice, communication and quality of life within the cohort and identify potential intervention targets to prevent post-intubation laryngeal injuries. Subjects will be recruited from Penn's Otorhinolaryngology …
This study investigates the use of intraoperative imaging to better visualize ovarian cancer during surgery. The study aims to enhance the ability to see cancerous tumors in real-time during surgical procedures.The focus of this study is to evaluate the effectiveness of using fluorescent probes that target specific cancer markers, such …
The goal of this prospective study is to evaluate the safety and effectiveness of the da Vinci Xi Surgical System, instruments, and accessories in Nipple Sparing Mastectomy, otherwise known as NSM procedures.
Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol
Women treated for primary breast cancer who undergo breast conservation therapy face an increased risk of developing a second breast cancer in the ipsilateral and the contralateral breast. Although mammographic screening is recommended annually, the sensitivity of mammography is limited in these patients due to the post treatment changes from …
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