Search filters

Filters
Clear All

Phase

  • 10
  • 9
  • 18
  • 14
  • 1
  • 52
  • 112
  • 25
  • 1
  • 8
  • 103

Found 112 surgery trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Phase 3 Multicenter Study of Gleolan (Aminolevulinic Acid Hydrochloride) to Enhance Visualization of Tumor in Patients with Newly Diagnosed or Recurrent Meningiomas
18 years - 99 years
All genders
Phase 3
This study is designed to investigate the safety, diagnostic performance, and clinical usefulness of Gleolan for the real time detection and visualization of meningiomas during tumor resection surgery. Potential patients who sign informed consent will be screened for eligibility before receiving an oral solution of Gleolan 3 hours prior to …
99 years or below
All genders
The primary objective of the study is to assess adverse events (AEs) and serious adverse events (SAEs) in kidney transplant recipients previously treated with REGN5459 or REGN5458 in the R5459-RT-1944 study. The primary endpoint for this study is the incidence of AEs and SAEs over a 12-month period, starting at …
18 years - 99 years
All genders
Phase 1
Interventional
The purpose of this study is to test the ability of a new drug, BGB324, to get into the brain tumor (e.g.by crossing the blood brain barrier) in patients with recurrent glioblastoma who require surgery.
 A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence
18 years - 99 years
All genders
Phase 3
This is a study in participants with HER2-positive primary breast cancer who have received preoperative chemotherapy and HER2-directed therapy, including trastuzumab followed by surgery, with a finding of residual invasive disease in the breast and/or axillary lymph nodes
 The effect of Liposomal Bupivacaine on the quality of recovery in patients undergoing shoulder arthroscopy
18 years - 99 years
All genders
Phase 3
The research study is being conducted to see if using liposomal bupivacaine for the interscalene block will improve the patient pain control and the whole patient’s experience 48 hours after surgery when compared to using the regular Marcaine in addition to the dexamethasone.
 Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer
99 years or below
All genders
Phase 1
Surgery is the best treatment for patients with Stage I or II lung cancer; however, nearly 60% of patients have recurrence. Additional immunotherapeutic agents given before surgery may be greatly reduce recurrence. This is a Standard Phase I, 3+3 dose escalation trial designed to evaluate the safety and toxicity of …
99 years or below
All genders
PURPOSE: The overall objective of the project is to perform comparative metabolomics on frail and non-frail patients undergoing major surgery. We hypothesize that frail patients will have distinct baselines, suffer greater metabolic derangements, and recover more slowly than non-frail patients. Additionally, we hypothesize that those patients who undergo prehab will …
 Collection of Samples from the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance
45 years - 85 years
All genders
This study is designed to prospectively collect blood samples and clinical data from subjects that have a suspected advanced adenoma or have been newly diagnosed with colorectal cancer and scheduled for resection surgery, and subjects who are at average risk of colorectal cancer and who are scheduled for routine colonoscopy …
99 years or below
All genders
Phase 2
The main purpose of this study is to determine the rate of positive sentinel lymph nodes (i.e. the closest draining lymph node(s) to the primary melanoma site) and to test whether treatment with pembrolizumab before surgery to remove melanoma reduces the rate of positive sentinel lymph nodes in patients with …
 APOLLO: A Randomized Phase II Double-Blind Study of Olaparib versus Placebo Following Adjuvant Chemotherapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1  BRCA2 or PALB2 Mutation
18 years - 99 years
All genders
The purpose of this study is to compare the usual treatment alone to using one year of olaparib. We will enroll subject who have been diagnosed with pancreatic cancer and have undergone surgery to remove the cancer. Only patients who are found to have a BRCA1, BRCA2 or PALB2 mutation …
31 - 40 of 112