Found 112 surgery trials
A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The main purpose of this study is to test the safety and efcacy (how well it works) of an experimental intervention called VY-AADC02 on the severity of PD. VY-AADC02 involves placing a gene in the brain that programs brain cells to produce an enzyme (protein) called AADC (aromatic amino acid …
The main purpose of this study is to test the safety and efficacy (how well it works) of an experimental intervention called VY-AADC02 on the severity of PD. VY-AADC02 involves placing a gene in the brain that programs brain cells to produce an enzyme (protein) called AADC (aromatic amino acid …
To evaluate the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of VGT-309 to detect cancer utilizing near-infrared (NIR) fluorescence and histopathology results. 1. Sensitivity: defined as the probability that the tissue fluoresces when it is cancer, as confirmed by histology (TP/(TP+FN)) 2. Specificity: defined as the …
Patients will be recruited from within the Penn Medicine Abramson Cancer Center pool of patients. This sub-study is part of a larger research study that is testing experimental treatments for melanoma. This sub-study is testing experimental drugs when they are given before and/or after melanoma surgery. Subjects will be assigned …
This phase II/III trial compares the effect of adding chemotherapy before and after surgery versus after surgery alone (usual treatment) in treating patients with stage II-III gallbladder cancer. This study will determine whether giving chemotherapy before surgery increases the length of time before the cancer may return and whether it …
This research study is being conducted to evaluate a treatment approach that may make the pain or discomfort experienced following surgery less severe and decrease the length of time this pain or discomfort will last. Stress, pain and opioid medication use prior to surgery can make post-operative pain …
This study is a multicenter study of up to 300 subjects diagnosed with OSA who are being evaluated for airway surgery, including hypoglossal nerve stimulation. Subjects will undergo standard evaluation for airway surgery as part of standard of care. In addition, a simple, non-invasive measurement of the pharyngeal width (PW) …
The purpose of the research is to compare two commonly used treatment strategies for managing atrial fibrillation after cardiac surgery. Patients 18 yrs. or older are randomized within 7 days after scheduled to undergo coronary artery bypass grafting (CABG), also known as bypass surgery. Only patients that undergo isolated CABG …
NSAIDs like ibuprofen are pain relievers that are commonly used to reduce pain after dental procedures. Patients who have their impacted third molar teeth taken out usually experience pain one to three hours after surgery and require pain relievers for at least 2 days. Most people (about 70-90%) experience good …
The purpose of this registry is to collect real-time data for those patients who have aortic disease of their ascending (top) aorta and the aortic arch (curved area where the vessels that supply the brain with blood). The current treatment requires open surgery or a hybrid procedure (open surgery with …
