Found 116 surgery trials
A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
High Velocity Nasal Insufflation (Hi-VNI) Use in Upper Airway Surgery
The goals of this study are to establish the efficacy of Hi-VNI in upper airway surgery from the anesthesiologists' and surgeons' perspectives, and to describe the ideal patient and the ideal pathology as well as suitable clinical scenarios when this oxygenation technique should be selected.
Evaluating Changes in Perfusion to the Chest Wall During Cardiothoracic Surgery
The research study is being conducted to learn how violating the chest wall during Cardiothoracic surgery changes perfusion to the bone and soft tissue of the chest wall. Further, this study will investigate whether changes in perfusion are correlated with adverse clinical outcomes. If you agree to join the study, …
Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
COSMID is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. The goal of the COSMID trial is to answer the question: For patients with QoL-limiting diverticular disease, is elective colectomy more effective than best medical …
Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy
This study is being done to evaluate if participants with HER2-positive breast cancer who have no cancer remaining at surgery after 12 weeks of chemotherapy and two HER-targeting therapies eliminate further chemotherapy after surgery. Eligible subjects would be those with HER2-positive breast cancer.
Study to Determine if Phasix™ Mesh Helps Prevent Incisional Hernias That Can Occur After Abdominal Surgery
The purpose of this trial is to determine whether Phasix™ Mesh helps prevent incisional hernias that sometimes occur after abdominal surgery by strengthening the closure of the tissue and/or the incision following surgery.
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
This phase III trial tests two questions by two separate comparisons of therapies. The first question is whether enhanced therapy (apalutamide in combination with abiraterone + prednisone) added to standard of care (prostate radiation therapy and short term androgen deprivation) is more effective compared to standard of care alone in …
CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer
SGM-101 is a fluorochrome-labeled anti-carcino-embryonic antigen (CEA) monoclonal antibody. What this means is that part of SGM-101 is a chemical that is attracted to and will attach to the cells of your cancer. Another part of SGM-101 is a chemical that will glow when infrared light is shined on it. …
Nerve Transfers to Improve Upper Extremity Function and Quality of Life in Tetraplegic Patients
Peripheral nerve transfers in patients with cervical SCI will improve distal motor function, functional independence and patient quality of life. Nerve transfers have improved patient outcomes following brachial plexus injuries and more recently case reports have demonstrated exciting outcomes when utilized in patients with cervical SCI. The long-term objective of …
Study to Evaluate Imaging Feasibility, Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes Primary Tumors and Tumor Margins in Patients with Solid Tumors
The purpose of this research study is to learn about the safety and effectiveness of using ONM 100 to obtain images of primary tumors and metastatic lymph nodes in patients with solid tumors undergoing routine surgery. Adults at least 18 years of age with a Biopsy-confirmed diagnosis of primary or …
Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial
The purpose of this study is to evaluate if closing off the left atrial appendage (LAA) of your heart (a small-sack like structure that is part of the upper chamber of the heart) during scheduled heart surgery with a surgical device known as the AtriClip, reduces the risk of a …
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