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Found 383 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 RADVAX FOR RELAPSED/REFRACTORY NON-HODGKIN LYMPHOMA: A PHASE II TRIAL OF PEMBROLIZUMAB + LOW DOSE RADIOTHERAPY
18 years - 99 years
All genders
Phase 2
This study plans to treat subjects with pembrolizumab by infusion in combination with radiation therapy to see if the combination is an effective treatment for relapsed/refractory non-Hodgkin lymphoma. Radiation therapy is commonly used to treat relapsed/refractory non-Hodgkin lymphoma. Although pembrolizumab is FDA-approved for some cancers, including Hodgkin lymphoma, it is …
 Defining the role of germline genetic variants in gastric cancer tumorigenesis
99 years or below
All genders
The research study is being conducted to better understand factors that lead to gastric (stomach) cancer, including differences in our genes that may put some people at increased risk of developing gastric cancer compared to other people. Both people with increased risk as well as people with average risk of …
18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this study are to determine the maximum dose of FF-10832 that can be tolerated when taken in combination with pembrolizumab and to determine whether FF10832 taken by itself or in combination with pembrolizumab has anti-tumor activity.
99 years or below
All genders
Phase 1
Please see Protocol NUV-868-01, Section 3 (Objectives and Endpoints) Please see Protocol NUV-868-01, Section 3 (Objectives and Endpoints) Please see Protocol NUV-868-01, Section 3 (Objectives and Endpoints)
 A Trial of Endocrine Response in Women with Invasive Lobular Breast Cancer
18 years - 99 years
All genders
Phase 2
To study whether fulvestrant is more effective than anastrozole or tamoxifen in reducing Ki67 in ILC and whether that Ki67 reduction will correlate with alterations in expression of ER and ER-regulated genes. Differential Ki67 effect in this study will serve as a surrogate for outcome of ILC patients on endocrine …
 Testing novel drugs or drug combinations to treat breast cancer before surgery
18 years - 99 years
Female
A clinical trial to determine whether adding experimental agents to standard neoadjuvant paclitaxel (with or without trastuzumab), anthracycline, nad cyclosphosphamide increases the probability of pathologic complete response (pCR) over standard neoadjuvant chemotherapy for each biomarker signature established at trial entry, and to determine for each experimental agent used, the predictive …
99 years or below
All genders
PURPOSE: The aim of this study is to assess the feasibility of beta-hydroxybutyrate (BHB) supplementation in individuals who are undergoing a standard-of-care colonoscopy or flexible sigmoidoscopy in order to determine whether BHB supplementation is safe and tolerable, whether BHB supplementations increases serum BHB levels, and whether BHB supplementation leads to …
99 years or below
All genders
Phase 2
The goal of this study is to confirm that an investigational study drug, ASP1650, is both safe and effective as a treatment in participants with incurable, refractory germ cell tumors that have Claudin 6 (CLDN6) expression.
99 years or below
All genders
Phase 1
Please refer to Section 4 of the full protocol (Study Objectives and Endpoints) Please refer to Section 4 of the full protocol (Study Objectives and Endpoints) Please refer to Section 4 of the full protocol (Study Objectives and Endpoints)
 TIME- Text-based intervention to minimize the time burden of routine cancer care
18 years - 99 years
All genders
The research study is being conducted to evaluate and test a text message-based strategy to streamline care. Our text message-based triage would screen patients before they come to the clinic, allowing patients with no side effects and normal bloodwork to get their infusion without having to wait. To ensure this …
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