Found 383 Neoplasms trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study is open to adults with advanced cancer in the biliary tract, pancreas, lung, or bladder for whom previous treatment was not successful or no treatment exists, to find out whether a medicine called BI 907828 helps. BI 907828 is a so-called MDM2 inhibitor that is being developed to …
This study has a mono therapy arm and a combination therapy arm. The main purpose of the mono therapy arm is to test the safety and tolerability of ART4215 in humans. The main purpose of the combination therapy arm is to test ART4215 compared to and in combination with talazoparib.
The purpose of this study is to confirm that tumor alterations and biomarkers can direct biologic therapies and potentially enhance survival outcomes in women with Endometrial Cancer
To evaluate an investigational, personalized adjuvanted vaccine, GEN-009, that is being developed for the treatment of patients with solid tumors. A personalized vaccine, consisting of between 4 to 20 synthetic long peptides, will be generated for each patient and shall be administered as an adjuvanted vaccine, with the adjuvant Hiltonol.
The purpose of this study is to test the safety and effectiveness of domvanalimab when given together with zimberelimab with and without chemotherapy. We would like to rely on WCG the IRB of record for this study.
This research study is designed to learn more about the safety and effectiveness of lurbinectedin given to individuals who have been diagnosed with advanced (metastatic and/or unresectable) solid tumors.
An Open-Label, Multicenter, First-in-Human, Dose-Escalation Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas.
This phase II LUNG-MAP treatment trial studies how well selpercatinib works in treating patients with RET fusion-positive non-small cell lung cancer that is stage IV or has come back (recurrent). Selpercatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth
This study investigates the effects of an investigational medication on cancer and non-cancer conditions. The purpose is to understand how the treatment affects individuals with these conditions.The study focuses on evaluating the safety and effectiveness of the investigational medication in participants with different health conditions.Who can participate: Participants must meet …
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