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Found 357 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Study of CDK-002 (exoSTING) in Subjects with Advanced/Metastatic  Recurrent  Injectable Solid Tumors  with Emphasis on Squamous Cell Carcinoma of the Head and Neck  Triple Negative Breast Cancer  Anaplastic Thyroid Carcinoma  and Cutaneous Squamous Cell Carcinoma
18 years - 99 years
All genders
Phase 1
Interventional
Consider this study if you have cancer that is considered advanced and/or has spread to other parts of your body. You have received treatment for your cancer but your cancer has come back or has worsened following that treatment. As part of this study, you will complete routine procedures that …
99 years or below
All genders
Phase 1
Interventional
This study is being done to determine how well the study drug, BGB-290, gets into the brain tumor and to confirm if we can continuously and safely give BGB-290 and temozolomide as a combination treatment after surgery. We are testing a dose of temozolomide once a day combined with the …
 A Phase 1/2a Study to Evaluate the Safety, Tolerability, Immunogenicity, andAnti-Tumor Activity of GEN-009 Adjuvanted Vaccine in Adult Patients with Selected SolidTumors
18 years - 99 years
All genders
To evaluate an investigational, personalized adjuvanted vaccine, GEN-009, that is being developed for the treatment of patients with solid tumors. A personalized vaccine, consisting of between 4 to 20 synthetic long peptides, will be generated for each patient and shall be administered as an adjuvanted vaccine, with the adjuvant Hiltonol.
99 years or below
All genders
mNET is commonly treated with TACE or TACE. mNET cells can survive TACE or TARE ischemic conditions. In this study, we will biopsy mNETs being treated with TACE or TARE prior to treatment, after treatment, and again at recurrence to characterize the metabolic, immunologic, and genetic profile of the cells …
 Study of lurbinectedin efficacy and safety in participants with advanced or metastatic solid tumors
18 years - 99 years
All genders
Phase 2
Interventional
This research study is designed to learn more about the safety and effectiveness of lurbinectedin given to individuals who have been diagnosed with advanced (metastatic and/or unresectable) solid tumors.
18 years - 99 years
All genders
Phase 1
Interventional
This study involves research of an investigational therapy called SynKIR-110. SynKIR-110 is CAR T cell therapy. CAR T cell therapy is a type of treatment in which a patient’s T cells (white blood cells that are a part of the immune system) are changed in a laboratory so they can …
 S1900B A Phase II Study of LOXO-292 in Patients with RET Fusion-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)
18 years - 99 years
All genders
Phase 2
This phase II LUNG-MAP treatment trial studies how well selpercatinib works in treating patients with RET fusion-positive non-small cell lung cancer that is stage IV or has come back (recurrent). Selpercatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth
 Study of INBRX-109 in Subjects with Locally Advanced or Metastatic Solid Tumors Including Sarcomas
18 years - 99 years
All genders
An Open-Label, Multicenter, First-in-Human, Dose-Escalation Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas.
99 years or below
All genders
See protocol section 2 See protocol section 2 See protocol section 4
99 years or below
All genders
See protocol section 2 See protocol section 2 See protocol section 4
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