Search filters

Filters
Clear All

Phase

  • 33
  • 92
  • 1
  • 77
  • 37
  • 1
  • 93
  • 357
  • 158
  • 13
  • 16
  • 328
  • 354
  • 3

Found 357 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)
18 years or above
All genders
Phase 1
Interventional
This is a first-in-human, multicenter, open-label, phase 1 study to evaluate the safety, PK, PD and preliminary efficacy of STX-0712 in patients with advanced CMML and AML for whom there are no further treatment options known to confer clinical benefit.
 Evaluating the Safety and Tolerability of XmAb 18087 in Subjects with Advanced Neuroendocrine and Gastrointestinal Stromal Tumors (DUET-1)
12 years - 99 years
All genders
The primary purposes of this research study is to determine the safety and tolerability of the investigational drug, XmAb18087, and if the XmAb18087 works in treating tumors like you have and side effects from XmAb18087, to find the best dose for treating your type of tumor. XmAb18087 is an investigational …
 AMC 083 / UPCC 12716: Tissue Acquisition for Analysis of Prognostic Factors  Immunology  and Genetic Progression of HIV-1 Associated Malignancies
18 years - 99 years
All genders
The main purpose of this study is to collect tissue from people diagnosed with HIV-associated cancer. We will use these samples to look for genetic changes associated with HIV- and other virus-related cancers. This may lead to better ways of preventing, detecting, and treating HIV-associated cancers.
 Whole-Brain Spectroscopy Guided Personalized Delivery of Tumor Treating Fields in Glioblastoma Patients
22 years - 99 years
All genders
The research study is for Glioblastoma (GBM) patients beginning Optune, a therapy that uses - tumor treating fields (TTFields). As a part of this study participants will either receive Optune with standard treatment array mapping from MR imaging or an alternative treatment array mapping based on advanced MR imaging also …
18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this research study is to learn if the investigational study drug, pegsitacianine, helps in seeing the primary lung cancer tumor and identifying any additional cancerous tissue present in the lung for removal at the time of standard of care cancer surgery. Each participant will receive a single …
 Precision Promise Platform Trial for Metastatic Pancreatic Cancer
99 years or below
All genders
Precision Promise is a multi-center, seamless Phase 2/3 platform trial designed to evaluate multiple regimens in metastatic pancreatic cancer. The goal of the platform is to find effective therapies for pancreatic cancer. The platform will rapidly and efficiently test multiple novel drugs and combinations compared to standard of care therapy …
 Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver
18 years - 99 years
All genders
Phase 2
Interventional
This trial studies how well pevonedistat alone or in combination with chemotherapy (paclitaxel and carboplatin) works in treating patients with bile duct cancer of the liver. Pevonedistat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as …
18 years - 99 years
Female
Interventional
The purpose of this study is to test a new scanner device that combines two types of imaging called Breast Positron Emission Tomography (BPET) and Digital Breast Tomosynthesis (DPT) for imaging of a radioactive imaging drug called 18F-Fluoroestradiol (FES), as a diagnostic device for imaging estrogen receptor (ER) positive breast …
99 years or below
All genders
The purpose of this program is to allow patients who, in consultation with their treating physician, feel it is in their best interest to continue to receive olaratumab. Only patients with soft tissue sarcoma who are already being treated with olaratumab may enter this program.
 TACE Ax HCQ: Phase IB Study of Hepatic Chemoembolization Plus Axitinib and Hydrochlorquine for Liver-Dominant Metastatic Adenocarcinoma Of The Colon And Rectum
18 years - 99 years
All genders
Phase 1
Interventional
Liver metastases are a leading cause of death among patients with metastatic colorectal cancer. Duration of disease control is short following 2nd-line or later systemic therapy. Liver-directed therapy such as TACE has a higher response rate and improves PFS, but the benefit is still limited. Cancer cells escape ischemic cell …
221 - 230 of 357