Found 357 Neoplasms trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The research study is being conducted secondary and after your completion of the primary study (Effect of Radiation Therapy on Sleepiness and Activity in Prostate and Breast Cancer Patients). The purpose of the current study is to assess the effectiveness of a behavioral treatment for insomnia (also known as Cognitive …
The purpose of this research is to collect clinical information and research tissue samples (blood, tissue, and stool) from patients receiving standard treatment for metastatic triple-negative breast cancer to help researchers better understand the use of immunotherapy in breast cancer.
This is a randomized phase 2 open label study of sacituzumab govitecan +/- pembrolizumab for patients with PD-L1-negative (PD-L1-) metastatic triple negative breast cancer (TNBC), who have not received prior therapy for metastatic breast cancer and who have not received a prior PD-1/L1 inhibitor
This phase III trial compares denosumab to placebo for the prevention of breast cancer in women with a BRCA1 germline mutation. Research has shown that denosumab may also reduce the risk of developing breast cancer in women carrying a BRCA1 germline mutation.
The purpose of the study is to evaluate whether SAR439859 (an experimental hormonal treatment), in combination with palbociclib is a better option compared to letrozole (a standard hormonal treatment), in combination with palbociclib, in terms of efficacy and tolerance for treating patients with ER (+), HER2 (-) breast cancer. Eligible …
LOXO-292 is a highly potent and specific inhibitor of the RET RTK, with minimal inhibition of other kinase and non-kinase targets, and therefore may be of benefit to patients with tumors (such as NSCLC, MTC, PTC, and colon or breast carcinomas) that harbor RET alterations and/or depend on RET activation. …
The goal of this prospective study is to evaluate the safety and effectiveness of the da Vinci Xi Surgical System, instruments, and accessories in Nipple Sparing Mastectomy, otherwise known as NSM procedures.
![IMAGING OF IN VIVO SIGMA-2 RECEPTOR EXPRESSION WITH [18F]ISO-1 POSITRON EMISSION TOMOGRAPHY (PET/CT) IN METASTATIC BREAST CANCER](/media/img/trial_thumbnails/PET-CT_Scanner_2_1okELH6.jpg)
Patients with metastatic breast cancer, that is biopsy proven or clinically documented by standard imaging (e.g. CT, MRI, Bone Scan, Ultrasound, FDG PET/CT), may be eligible for this study. Patients may participate in this study, if they are at least 18 years of age. We anticipate enrolling up to 30 …
This is a phase 1 study that enrolls subjects with metastatic pancreatic adenocarcinoma. The purpose of this study is to learn about the safety and efficacy of a combination of 4 study drugs: ipilimumab (ipi), nab-paclitaxel (nP), gemcitabine (gem), and hydroxychloroquine (HCQ). This is an open-label, non-randomized, exploratory platform trial …
The research study is being conducted to evaluate the safety and effectiveness of MK-6482 when compared to treatment with everolimus for renal cell carcinoma.
