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Found 387 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Identification of neoantigen-specific T cell responses in cancer patients within the Penn Medicine BioBank

Identification of neoantigen-specific T cell responses in cancer patients within the Penn Medicine BioBank

18 years - 90 years
All genders
You are being asked to participate in this research investigation because you have expressed an interest in participating in a study to better understand how the immune cells of the body recognize and fight cancer.

Imaging of Primary or Recurrent Breast Cancer with 18F-FluorThanatrace Positron Emission Tomography (PET/CT)

All genders
Phase 1
This study recruits participants directly from Penn Medicine clinics, during time of their clinical biopsies. Up to 40 participants with known or suspected primary or metastatic breast cancer who meet eligibility requirements for this study will undergo FTT PET/CT study imaging. Each PET/CT scan will include an injection of up …

Study of Drug Serabelisib in Combination with an Insulin Suppressing Diet in Subjects with Cancer

18 years - 99 years
All genders
Phase 1
Interventional
The main purpose of this research is to try and find a better way to treat cancer. Specifically, this research will study how participants tolerate and might benefit from combining a special diet that is low in carbohydrates and high in fat with a drug intended to treat cancer (called …
 Integrating Clinical Trials and Real-World Endpoints Data (ICAREdata) Capture and Standardization Companion Study

Integrating Clinical Trials and Real-World Endpoints Data (ICAREdata) Capture and Standardization Companion Study

18 years - 99 years
All genders
Observational
The purpose of this study is to understand how we might better collect health information that tells us how subjects study treatment for their cancer is working, and how their overall health is changing over time. This is a companion study to protocol A071701.

Pragmatic Clinical Trial Comparing Smoking Cessation Interventions among Underserved Patients who are referred for Lung Cancer Screening

All genders
Phase 3
Low-dose computed tomography (LDCT) screening reduces mortality among current and former smokers at high risk for lung cancer, and is widely recommended by national guidelines. LDCT also increases access to care and thus provides an opportunity to deliver smoking cessation interventions to current smokers in conjunction with this screening. As …
 The Association Between CBT-I Dose and Innate Immunity in Insomnia and Fatigue in Prostate Cancer Patients

The Association Between CBT-I Dose and Innate Immunity in Insomnia and Fatigue in Prostate Cancer Patients

18 years - 99 years
All genders
The research study is being conducted secondary and after your completion of the primary study (Effect of Radiation Therapy on Sleepiness and Activity in Prostate and Breast Cancer Patients). The purpose of the current study is to assess the effectiveness of a behavioral treatment for insomnia (also known as Cognitive …
 Phase I Trial of GFR4 CART Cells in Adult Patients with Recurrent or Metastatic Medullary Thyroid Cancer

Phase I Trial of GFR4 CART Cells in Adult Patients with Recurrent or Metastatic Medullary Thyroid Cancer

18 years - 99 years
All genders
Phase 1
This is an open-label phase 1 study to assess the safety and feasibility of autologous T cells expressing a single-chain scFv targeting GFRa4 with tandem TCR/CD3 and 4-1BB (TCR/4-1BB) costimulatory domains (referred to as CART-GFRa4) in patients with incurable medullary thyroid cancer (MTC). This is a Phase 1 study evaluating …
 Retreatment with CTL019/CTL119 in Patients with Late Relapse of B-Cell Lymphomas

Retreatment with CTL019/CTL119 in Patients with Late Relapse of B-Cell Lymphomas

18 years - 99 years
All genders
Phase 1
Interventional
The primary objective of this study is to evaluate the safety of retreatment of patients with CTL019/CTL119 therapy who have experienced late relapse of lymphoma.
 UPCC 12119: An Exploratory Biomarker Study of Metastatic Triple-Negative Breast Cancer Patients Treated with Immune Checkpoint Inhibitors

UPCC 12119: An Exploratory Biomarker Study of Metastatic Triple-Negative Breast Cancer Patients Treated with Immune Checkpoint Inhibitors

18 years - 99 years
All genders
Interventional
The purpose of this research is to collect clinical information and research tissue samples (blood, tissue, and stool) from patients receiving standard treatment for metastatic triple-negative breast cancer to help researchers better understand the use of immunotherapy in breast cancer.
 Study of Regn4336 administered Alone or in Combination with Cemiplimab in Patients with Metastatic Castration-Resistant Prostate Cancer

Study of Regn4336 administered Alone or in Combination with Cemiplimab in Patients with Metastatic Castration-Resistant Prostate Cancer

18 years - 99 years
Male
Interventional
This research study is designed to learn more about the safety and effectiveness of REGN4336 alone or in combination with cemiplimab given to individuals who have been diagnosed with Prostate Cancer.
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