Found 41 Pain trials
A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
This phase III trial tests two questions by two separate comparisons of therapies. The first question is whether enhanced therapy (apalutamide in combination with abiraterone + prednisone) added to standard of care (prostate radiation therapy and short term androgen deprivation) is more effective compared to standard of care alone in …
Bupivacaine RCT- Bupivacaine as Adjuvant for Post-operative Pain in Mohs micrographic surgery
The research study is being conducted to find the best ways to reduce pain after Mohs surgery. The research team hopes to learn if adding additional numbing medication at the end of surgery will help reduce pain afterwards. Penn Medicine patients having Mohs surgery will be invited to participate in …
A pilot randomized control trial to determine the feasibility of a hypnosis intervention for the treatment of bladder pain syndrome/interstitial cystitis.
The purpose of this research study is determine the feasibility of a hypnosis intervention to women with bladder pain syndrome. We also plan to assess the effect of hypnotic words and suggestions on brain function. Hypnotherapy has been studied in other chronic pain conditions and has been shown to be …
HOPE Trial
HOPE is a randomized clinical trial that will evaluate approaches to reducing pain and opioid use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage renal disease. The hypothesis is that pain coping skills training will be effective at reducing pain and opioid use, and that buprenorphine …
The effect of Liposomal Bupivacaine on the quality of recovery in patients undergoing shoulder arthroscopy
The research study is being conducted to see if using liposomal bupivacaine for the interscalene block will improve the patient pain control and the whole patient’s experience 48 hours after surgery when compared to using the regular Marcaine in addition to the dexamethasone.
Duplicate trial test 2
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia (MIH). The goal is to determine if pre-operative application of SDF results in improved local anesthesia and decrease …
Single-Patient Expanded Access Protocol for Tradipitant in a Single Patient with Gastroparesis.”
This study is not open to participants that have not completed the induction study. This treatment plan is for a single patient with gastroparesis who has requested expanded access to tradipitant. Gastroparesis is a condition where the stomach is unable to perform its normal functions. Individuals with gastroparesis have delayed …
RhIMAB Study
Participation in this research study is presented as a voluntary option to those women presenting at Penn Medicine and choosing medication abortion. The research team seeks to asses the value of blood typing and the provision of Rh immune globulin to women choosing medication abortion at 10 weeks and 0 …
Study of Daratumumab with Dose-Adjusted EPOCH in Newly Diagnosed Plasmablastic Lymphoma
Patients with plasmablastic lymphoma are potential participants of this research trial. Patients with a type of B-cell non-Hodgkin lymphoma (NHL) will be invited from Penn Medicine practices. This research study is designed to test the safety of daratumumab, a drug added to the standard lymphoma treatment when given to individuals …
The Role of the Microbiome in Inter-Individual Variability in NSAID Disposition and Response
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in the treatment of pain and inflammation. Mounting evidence indicates that rectal administration of NSAIDs is also effective in preventing pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP) by an unknown mechanism. Alterations in the salivary and fecal microbiome have been observed in patients with …
Please choose between Voice or SMS based delivery of verification code
or