Found 41 Pain trials
A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion
Degenerative disc disease (DDD) is a common disorder of the lumbar spine. Clinically, DDD causes discogenic back pain and may cause related radicular, neuropathic, claudicatory, and referred pain. This study intends to demonstrate the safety and efficacy of KUR-113 Bone Graft (TGplPTH1-34 in fibrin) versus local autograft.
Prescribed opioid induced brain damage in chronic pain patients
Opioids activate the limbic system and results in acute cell injury hippocampal atrophy. Thespecific aims of this proposal are to test the hypotheses that humans with chronic pain on longterm,high-dose opioids: 1. Will demonstrate smaller hippocampal volumes by MRI. 2. Willperform more poorly on neuropsychological tests of memory and associated …
Pilot Study of a Multi-System Analysis of Opioid Receptor Binding
The purpose of this research is to learn more about mu opioid receptor (MOR) binding in the brain and body. This study will enroll up to 60 adults in three cohorts of up to 20 participants each: Cohort 1: Subjects with a lifetime diagnosis of Opioid Use Disorder (OUD) on …
Investigational COVID-19 Vaccine Trial
This clinical research trial is being conducted to find out whether the administration of two investigational dMab products (not approved by the US FDA) with an investigational device is safe, tolerated, and can produce enough antibodies in your blood that may indicate the ability to prevent infection of COVID-19.
The FIRE Trial: Reducing patient memory recall in the burning mouth patient population
The purpose of this study is to collect real-time data, such as pain symptoms and exercise habits, to investigate the factors that influence burning mouth symptoms. Participants will be asked to complete questionnaires during the in-person visits and you will receive up to three, random daily notifications from your smartphone …
Evaluation of Corneal Confocal Microscopy in Ocular Surface Disease and/or Neuropathic Pain Patients
The purpose of this study is two-fold. Since there is currently no FDA approved software to analyze these images, the images taken will be used to help improve and refine current software, or help develop new software, in the hopes that it will be approved by the FDA. The images …
A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.
The purpose of this study is to evaluate the safety and efficacy of CNTX-6970. The target population is adults between 40 - 90 years old who have moderate to severe knee pain related to OA. The study drug is being compared to Celebrex, an FDA approved drug used to treat …
Pre-op CBT to Reduce the Risk for Development of Chronic Post-surgical Pain in Patients Undergoing Total Knee Arthroplasty
This research study is being conducted to evaluate a treatment approach that may make the pain or discomfort experienced following surgery less severe and decrease the length of time this pain or discomfort will last. Stress, pain and opioid medication use prior to surgery can make post-operative pain …
Study to evaluate SAF312 eye drops in the treatment of post-operative corneal induced chronic pain (CICP) following Photorefractive Keratectomy (PRK) or Laser-assisted in Situ Keratomileusis (LASIK) surgeries
Many patients suffer from acute ocular pain due to different problems, however there is no available treatment for chronic eye pain (long lasting eye pain). Very often eye pain is reported after surgical procedures, like PRK and LASIK. Up to 60% of patients continue to have chronic pain beyond one …
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