A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Degenerative disc disease (DDD) is a common disorder of the lumbar spine. Clinically, DDD causes discogenic back pain and may cause related radicular, neuropathic, claudicatory, and referred pain. This study intends to demonstrate the safety and efficacy of KUR-113 Bone Graft (TGplPTH1-34 in fibrin) versus local autograft.
This study is not open to participants that have not completed the induction study. This treatment plan is for a single patient with gastroparesis who has requested expanded access to tradipitant. Gastroparesis is a condition where the stomach is unable to perform its normal functions. Individuals with gastroparesis have delayed …
Opioids activate the limbic system and results in acute cell injury hippocampal atrophy. Thespecific aims of this proposal are to test the hypotheses that humans with chronic pain on longterm,high-dose opioids: 1. Will demonstrate smaller hippocampal volumes by MRI. 2. Willperform more poorly on neuropsychological tests of memory and associated …
The purpose of this research is to learn more about mu opioid receptor (MOR) binding in the brain and body. This study will enroll up to 60 adults in three cohorts of up to 20 participants each: Cohort 1: Subjects with a lifetime diagnosis of Opioid Use Disorder (OUD) on …
This clinical research trial is being conducted to find out whether the administration of two investigational dMab products (not approved by the US FDA) with an investigational device is safe, tolerated, and can produce enough antibodies in your blood that may indicate the ability to prevent infection of COVID-19.
This phase III trial tests two questions by two separate comparisons of therapies. The first question is whether enhanced therapy (apalutamide in combination with abiraterone + prednisone) added to standard of care (prostate radiation therapy and short term androgen deprivation) is more effective compared to standard of care alone in …
This study is intended to demonstrate the contraceptive efficacy of relugolix combination therapy. Myovant is developing relugolix combination therapy for the indications of the management of heavy menstrual bleeding associated with uterine fibroids and pain associated with endometriosis.
Participation in this research study is presented as a voluntary option to those women presenting at Penn Medicine and choosing medication abortion. The research team seeks to asses the value of blood typing and the provision of Rh immune globulin to women choosing medication abortion at 10 weeks and 0 …
The purpose of this study is to evaluate the safety and efficacy of CNTX-6970. The target population is adults between 40 - 90 years old who have moderate to severe knee pain related to OA. The study drug is being compared to Celebrex, an FDA approved drug used to treat …