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Found 40 Pain trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 90 years
All genders
Phase 2
The purpose of this study is to see whether a drug called naltrexone improves health-related quality of life in patients with vasculitis. Naltrexone is a prescription drug approved for a different reason at a higher dose than the dose used in this study. However, “low dose naltrexone” is widely used, …
18 years or above
All genders
Interventional
Compared to the general population, diabetic patients have a significantly higher rate of inadequate bowel preparation. The European Society of Gastrointestinal Endoscopy (ESGE) guideline recommends polyethylene glycol (PEG) as the preferred bowel-cleansing agent, but there is currently no standardized bowel preparation protocol specifically for diabetic patients. Previous studies have shown …
 Evaluation of Transcatheter Aortic Valve Replacement Compared to SurveilLance for Patients with AsYmptomatic Severe Aortic Stenosis
99 years or below
All genders
The study is evaluating the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve (THV) in comparison with clinical monitoring in asymptomatic patients over the age of sixty five that have be diagnosed with severe calcific narrowing of the aortic valve (aortic stenosis). Patients will be determined asymptomatic …
18 years or above
All genders
Observational
This study investigates the use of short femoral stems in hip arthroplasty for patients with primary hip osteoarthritis or osteonecrosis. The purpose of this study is to evaluate the outcomes when these stems are implanted through a minimally invasive anterior approach.The study focuses on understanding the safety and effectiveness of …
99 years or below
All genders
The primary objective of the study is to evaluate the safety and effectiveness of the NEUWAVETM FLEX MC Microwave Ablation System and Accessories used in transbronchial ablation procedures for adult subjects with oligometastatic tumors ( 2cm) in the lung. Technique Efficacy: Ablation of the target tumor(s) with the ablation zone …
18 years or above
All genders
Phase 2
Interventional
This study investigates the safety and tolerability of an investigational medication applied to digital ulcers in patients with systemic sclerosis. Systemic sclerosis is a rare condition that causes hard, thickened areas of skin and can affect internal organs and blood vessels.The study focuses on evaluating the safety of the investigational …
99 years or below
All genders
Phase 3
This is a Phase 3, open-label, multi-center trial to evaluate the long-term safety, efficacy, and immunogenicity of up to four continuous treatment cycles of daxibotulinumtoxinA (DAXI) for injection at doses of 125 U, 200 U, 250 U, or 300 U in adults with isolated cervical dystonia (CD). Approximately 290 adult …
 To Serenade or To Sedate? That is Still The Question - A Followup Trial On Anxiolytic Options Before Peripheral Nerve Blocks
99 years or below
All genders
The research study is being conducted to determine if there are differences in anxiety scores, heart rate, blood pressure, and oxygen status when using sedation medication versus the patient's choice of listening to music while undergoing a peripheral nerve block before his or her surgery. The patient will either receive …
 PTSD Treatment Study
18 years - 45 years
Female
Phase 2
Have you experienced a traumatic event that affected your life significantly? You may be eligible to participate in a study conducted by the Center for the Treatment and Study of Anxiety at the University of Pennsylvania.In this study we will investigate the influence of gonadal hormones on fear acquisition and extinction …
 Chronic insomnia and CSF markers of dementia
30 years - 59 years
All genders
The purpose of this study is to identify the relationship between chronic sleep disturbance and proteins in spinal fluid that are related to dementia and a molecule called orexin that helps regulate wakefulness and appetite in the brain. Individuals with sleep problems and good sleepers will be asked to participate.
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