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Found 38 Pain trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion
18 years - 75 years
All genders
Phase 2
Interventional
Degenerative disc disease (DDD) is a common disorder of the lumbar spine. Clinically, DDD causes discogenic back pain and may cause related radicular, neuropathic, claudicatory, and referred pain. This study intends to demonstrate the safety and efficacy of KUR-113 Bone Graft (TGplPTH1-34 in fibrin) versus local autograft.
 Single-Patient Expanded Access Protocol for Tradipitant in a Single Patient with Gastroparesis.”
18 years - 99 years
All genders
Interventional
This study is not open to participants that have not completed the induction study. This treatment plan is for a single patient with gastroparesis who has requested expanded access to tradipitant. Gastroparesis is a condition where the stomach is unable to perform its normal functions. Individuals with gastroparesis have delayed …
18 years - 50 years
All genders
Opioids activate the limbic system and results in acute cell injury hippocampal atrophy. Thespecific aims of this proposal are to test the hypotheses that humans with chronic pain on longterm,high-dose opioids: 1. Will demonstrate smaller hippocampal volumes by MRI. 2. Willperform more poorly on neuropsychological tests of memory and associated …
100 years or below
Female
test
 Pilot Study of a Multi-System Analysis of Opioid Receptor Binding
18 years - 50 years
All genders
This study investigates opioid receptor binding in the brain and body. It aims to understand how these receptors, which are involved in pain reduction and reward experiences, function in different individuals.The study focuses on measuring the binding of a specific type of opioid receptor using a PET/CT scan. This involves …
 Investigational COVID-19 Vaccine Trial
18 years - 60 years
All genders
Phase 1
This clinical research trial is being conducted to find out whether the administration of two investigational dMab products (not approved by the US FDA) with an investigational device is safe, tolerated, and can produce enough antibodies in your blood that may indicate the ability to prevent infection of COVID-19.
18 years or above
Male
Phase 3
Interventional
This study investigates prostate cancer that has returned after surgery. The purpose is to see if adding investigational medication and targeted radiation to standard treatment works better for patients with a rise in PSA levels after prostate cancer surgery.The study focuses on evaluating the effectiveness of additional treatments based on …
18 years - 50 years
Female
Phase 3
This study is intended to demonstrate the contraceptive efficacy of relugolix combination therapy. Myovant is developing relugolix combination therapy for the indications of the management of heavy menstrual bleeding associated with uterine fibroids and pain associated with endometriosis.
 RhIMAB Study
18 years - 99 years
All genders
Participation in this research study is presented as a voluntary option to those women presenting at Penn Medicine and choosing medication abortion. The research team seeks to asses the value of blood typing and the provision of Rh immune globulin to women choosing medication abortion at 10 weeks and 0 …
 A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.
40 years - 90 years
All genders
Interventional
The purpose of this study is to evaluate the safety and efficacy of CNTX-6970. The target population is adults between 40 - 90 years old who have moderate to severe knee pain related to OA. The study drug is being compared to Celebrex, an FDA approved drug used to treat …
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