Found 560 Barrett's Esophagus trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
To evaluate the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of VGT-309 to detect cancer utilizing near-infrared (NIR) fluorescence and histopathology results. 1. Sensitivity: defined as the probability that the tissue fluoresces when it is cancer, as confirmed by histology (TP/(TP+FN)) 2. Specificity: defined as the …
This study will measure the amount of a protein in the brain known as tau using an imaging procedure called Positron Emission Tomography (PET/CT). Findings from this study lead to a better understanding of factors that influence the course of Alzheimer’s and other diseases of aging. Participation in this study …
This is a first in human, phase 1 trial of BIIB105, which is a novel ASO, in patients with Amyotrophic lateral sclerosis (ALS) and ALS associated with ataxin-2 (ATXN2) poly-CAG expansion (polyQ-ALS). BIIB105 will be administered via fluoro-guided LP up to 5 times over approximately 3 months. Subjects will undergo …
This study is a multicenter study of up to 300 subjects diagnosed with OSA who are being evaluated for airway surgery, including hypoglossal nerve stimulation. Subjects will undergo standard evaluation for airway surgery as part of standard of care. In addition, a simple, non-invasive measurement of the pharyngeal width (PW) …
The purpose is to validate the Huxley Sansa device and automated scoring algorithm for detecting SDB events compared to the reference standard in-lab PSG. Participants will be recruited from Penn patients age 18+. This is a multi-site, sponsored study where Penn will rely on a central IRB, with enrollment across …
The purpose of this study is to see how safe the study medicine, IGV-001 plus standard of care (SOC), is and to compare IGV-001 with placebo (only standard of care) to see if it works in slowing GBM tumor regrowth. Participants for this study will be recruited from the patient …
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in the treatment of pain and inflammation. Mounting evidence indicates that rectal administration of NSAIDs is also effective in preventing pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP) by an unknown mechanism. Alterations in the salivary and fecal microbiome have been observed in patients with …
The POSEIDON study is a multi-center, prospective, single arm, crossover pivotal study enrolling up to 60 pivotal cohort patients and up to 30 additional Roll-in patients with refractory or recurrent ascites at up to 15 sites. Pivotal cohort patients will undergo a 3-month pre-implant observation phase after enrollment, followed by …
This dual-site, double-blinded, randomized, sham-controlled, crossover study is to assess the safety, feasibility, and preliminary efficacy of SEEG-guided multi-lead DBS in 10 participants suffering from severe symptoms of chronic, treatment-refractory OCD. Stage 1: Invasive SEEG Monitoring and Recovery Goal: To perform stimulation mapping studies and SEEG recordings, that aid in …
The primary objective of the study is to assess the effect of preventing preservation-related graft injury with the use of the metra® device in enrolled subjects. The single-arm continued access phase will be used to collect additional effectiveness and safety data to support the objectives and outcomes of the original …
