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Found 582 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Trial to evaluate the transcatheter tricuspid valve repair with the Edwards PASCAL Transcatheter Valve Repair System and optimal medical therapy (OMT) compared to OMT alone in patients with tricuspid regurgitation

18 years - 99 years
All genders
The research study is being conducted to determine the safety and effectiveness of an investigational device, the Edwards PASCAL Transcatheter Valve Repair System (hereinafter referred to as the PASCAL System), with optimal medical therapy (OMT) compared to optimal medical therapy alone in the treatment of patients with symptomatic, severe tricuspid …

Study to Assess Rifaximin Soluble Solid Dispersion (Ssd) Tablets for the Delay of Encephalopathy Decompensation in Cirrhosis (Red-C)

18 years - 85 years
All genders
Interventional
The purpose of this study is to see if a test medicine not yet approved for market, named Rifaximin SSD-40IR given Twice Daily, will help to delay the first episode of overt hepatic encephalopathy (OHE) requiring hospitalization, in patients with liver cirrhosis and how safe it is to use in …

Evaluating Investigational Drug AP-PA02 in Subjects with Cystic Fibrosis and Chronic Pulmonary Pseudomonas aeruginosa (Pa) Infection

18 years - 99 years
All genders
Phase 1
The purpose of this study is to evaluate an investigational drug called AP-PA02 as a possible treatment for individuals with cystic fibrosis (CF) and chronic pulmonary Pseudomonas aeruginosa (Pa) infection. There are 2 main parts to this study, Part 1 and Part 2. If you choose to take part in …

A Prospective and Retrospective Multi-Centre Post-Market Non-Interventional Study of Terumo Aortic* Cardiovascular Patches and Knitted and Woven Graft

All genders
A multicentre, non-interventional, post-market registry to collect safety and performance data on all commercially available knitted and woven grafts, and cardiovascular patches. Data will be collected both retrospectively and prospectively.

A5394: Safety Tolerability and Impact of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants with Both Chronic Hepatitis B and HIV

All genders
A5394 is a phase II, randomized, double-blind, placebo-controlled clinical trial to assess the safety, tolerability, and efficacy of 24 weeks of treatment with Selgantolimod (SLGN). Intensive PK sampling will be conducted in the first 12 participants who enroll into the study.

Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis (TOP-N53-02)

All genders
Phase 2
Interventional
The main goal of this clinical trial is to learn about how safe the new drug TOP-N53 solution is when it is applied to open wounds on the fingertip (digital ulcers) in people with an uncommon illness that results in hard, thickened areas of skin and additional problems with internal …
 A Randomized  Double-Blind  Parallel  Placebo-Controlled Study of the Efficacy  Safety and Tolerability of Dupilumab in Adult Patients with Active Eosinophilic Esophagitis

A Randomized Double-Blind Parallel Placebo-Controlled Study of the Efficacy Safety and Tolerability of Dupilumab in Adult Patients with Active Eosinophilic Esophagitis

1 years - 99 years
All genders
Phase 2
This is a multicenter, randomized, double-blind, placebo-controlled, 2-arm, parallel-group, proof-of-concept study. The primary purpose of this study is to evaluate the effect of dupilumab on relieving EoE clinical symptoms and reducing esophageal inflammation in adults. Currently there is no regulatory-approved endpoint for drug registration for this indication. Published clinical trials …
 FES PET/CT in Endocrine Refractory Breast Cancer

FES PET/CT in Endocrine Refractory Breast Cancer

18 years - 99 years
All genders
Patients with recurrent or metastatic ER+ breast cancer, who have failed prior endocrine therapy may be eligible for this study.  Patients may participate in this study, if they are at least 18 years of age, most participants will be receiving care at the clinical practices of the University of Pennsylvania. …
 TARGET-PBC: A 5-year Longitudinal Observational Study of Patients with Primary Biliary Cholangitis

TARGET-PBC: A 5-year Longitudinal Observational Study of Patients with Primary Biliary Cholangitis

18 years - 80 years
All genders
You are being asked to be in this research study because you have PBC (primary biliary cholangitis) which is an uncommon chronic cholestatic liver disease characterized by progressive inflammation and destruction of the interlobular bile ducts, ultimately leading to the development of biliary cirrhosis. 
 Multicenter  randomized  double-blind  parallel-group  add-on  superiority study to compare the efficacy and safety of ponesimod to placebo in subjects with active relapsing multiple sclerosis who are treated with dimethyl fumarate (Tecfidera )

Multicenter randomized double-blind parallel-group add-on superiority study to compare the efficacy and safety of ponesimod to placebo in subjects with active relapsing multiple sclerosis who are treated with dimethyl fumarate (Tecfidera )

All genders
Phase 3
This is a study to find out whether patients with active forms of Relapsing Multiple Sclerosis (RMS) who are treated with dimethyl fumarate (Tecfidera®) can be treated better by the addition of ponesimod (study drug). The purpose is also to evaluate the effect on disability and the safety of these …
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