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Found 582 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 MT-3921- Phase 2  Study to Assess the Efficacy and Safety of MT-3921 in Subjects with Acute Traumatic Cervical Spinal Cord Injury

MT-3921- Phase 2 Study to Assess the Efficacy and Safety of MT-3921 in Subjects with Acute Traumatic Cervical Spinal Cord Injury

18 years - 70 years
All genders
Phase 2
MT-3921 is an investigational monoclonal antibody therapy for patients with severe (AIS grade A-C) traumatic cervical spinal cord injury (SCIs). This study aims to compare the efficacy of MT-3921 to a placebo with regard to improving patients sensory and motor function and overall quality of life. Additionally this study aims …
 Sample Collection for Prospera Enhancement

Sample Collection for Prospera Enhancement

18 years - 99 years
All genders
Interventional
The research study is being conducted to learn how well a test called Prospera can detect rejection in a transplanted kidney after a biopsy. If results of the biopsy do not indicate rejection, the study team will follow your condition by reviewing your clinical visits for one year, at which …
 A randomized  double-blind  placebo-controlled clinical trial of once-daily inhaled molgramostim nebulizer solution in adult subjects with autoimmune pulmonary alveolar proteinosis (aPAP)

A randomized double-blind placebo-controlled clinical trial of once-daily inhaled molgramostim nebulizer solution in adult subjects with autoimmune pulmonary alveolar proteinosis (aPAP)

18 years - 99 years
All genders
Phase 3
The present confirmatory phase 3 trial will be conducted to further investigate the efficacy and safety of molgramostim in subjects with aPAP. Investigating how molgramostim improves lung pathology, pathophysiology, and health status in subjects with aPAP in a dose- frequency dependent fashion.
 A Randomized  Open Label Pilot Trial of a Biomarker Guided Strategy of Cardioprotection in Patients with Lymphoma or Breast Cancer Treated with Anthracyclines

A Randomized Open Label Pilot Trial of a Biomarker Guided Strategy of Cardioprotection in Patients with Lymphoma or Breast Cancer Treated with Anthracyclines

18 years - 99 years
All genders
Phase 1
You will be receiving anthracycline-based chemotherapy (Adriamycin/doxorubicin) as part of your cancer treatment plan. Although anthracycline-based chemotherapy is effective in treating cancer, it can damage your heart. This study has two goals. The first goal is to see if we can identify who is most at risk for this heart …
 A Clinical Study of NLY01 in Patient's With Early Parkinson's Disease

A Clinical Study of NLY01 in Patient's With Early Parkinson's Disease

30 years - 80 years
All genders
Phase 2
This is a study designed to assess the safety, tolerability and efficacy of NLY01 in subjects with early untreated Parkinson's disease (PD). Evidence suggests NLY01, a pegylated form of exenatide, may be beneficial in Parkinson's disease and is being developed as a potential treatment for neurodegenerative disorders.

Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

18 years - 99 years
All genders
Phase 2
This study is being done to evaluate if participants with HER2-positive breast cancer who have no cancer remaining at surgery after 12 weeks of chemotherapy and two HER-targeting therapies eliminate further chemotherapy after surgery. Eligible subjects would be those with HER2-positive breast cancer.
 INSIGHT: Investigation of Clot in Ischemic Stroke and Hematoma Evacuation

INSIGHT: Investigation of Clot in Ischemic Stroke and Hematoma Evacuation

18 years - 99 years
All genders
Observational
The aim of the study is to collect and analyze specimen from ischemic stroke patients undergoing thrombectomy procedures and from patients undergoing minimally invasive surgery for intracranial hematoma evacuation. Clot and blood specimen will be analyzed via histology, RNA sequencing, Single Nucleotide Polymorphisms (SNPs), and proteomic analysis.

Open label comparison of injectable buprenorphine (CAM2038 Brixadi ) and naltrexone (Vivitrol ) for opioid use disorder

All genders
Phase 2
Compare brain fMRI response to injectable extended-release buprenorphine (Brixadi, XR-BUP) and naltrexone (XR-NTX, Vivitrol) Our primary outcome combines adherence to treatment and the frequency of illicit opioid use during treatment. The primary outcome is a binary indicator of treatment success: Participants who provide 2 weekly UDS positive for opioids or …

Conduction System Pacing Optimized Therapy

18 years - 99 years
All genders
The research study is being conducted to determine the best mode of Cardiac Resynchronization Therapy (CRT) pacing for CRT patients. Participants will be asked to complete the following research procedure of a transthoracic echocardiogram (TTE) prior to their implant.

Study to Evaluate Safety and Efficacy of Ck3773274 in Adults with Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

18 years - 99 years
All genders
Phase 3
The purpose of this study is to compare the effects of CK-3773274, and placebo, on the exercise and health status of patients with oHCM. The safety and tolerability of CK-3773274 will also be studied.
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