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Found 114 Lymphocytic Leukemia, Acute trials

A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

100 years or below
Male
-For US: Aged 10 to 25 years on the day of inclusion ("10-25 years" means from the day of the 10th birthday to the day before the 26th birthday) For EU: Aged 42 to 89 days or 12 to 18 months or 10 to 50 years on the day of …
 Trial to Optimize Patients Selection for Endovascular Treatment in Acute Ischemic Stroke
99 years or below
All genders
Stroke can occur when a clot stops the flow of the blood in one of the arteries supplying the brain. This type of stroke, called ischemic stroke, can be treated alone or in a combination of drugs to dissolve the clot, devices to remove the clot (mechanical thrombectomy) or use …
99 years or below
All genders
Phase 3
The primary safety objective is a composite of the number of Major Adverse Events (MAEs) occurring through 30 days post-procedure compared to the rate in subjects treated with the Relay Thoracic Stent-Graft in the U.S. Pivotal Trial (P110038). The primary effectiveness objective is a composite of the number of effectiveness …
99 years or below
All genders
Phase 4
The primary study objective is to evaluate the rate of durable remission of relapsing disease activity, assessed serially both clinically and by MRI, from randomization through 48 months in participants with early relapsing multiple sclerosis who discontinue OCR after 12 and 24 months of treatment. Secondary objectives include: - Mechanistic: …
 RIDE+
18 years - 60 years
All genders
This research study will help us see whether providing medical services in a mobile unit will help persons who inject drugs (PWID) start and stay on anti-HIV medicines and medicines for opioid use disorder better.
 A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.
40 years - 90 years
All genders
Interventional
The purpose of this study is to evaluate the safety and efficacy of CNTX-6970. The target population is adults between 40 - 90 years old who have moderate to severe knee pain related to OA. The study drug is being compared to Celebrex, an FDA approved drug used to treat …
 Effects of psychiatric medications on decision-making study
18 years - 45 years
All genders
This study involves taking single doses of two common psychiatric medications – levodopa (Sinemet) and escitalopram (Lexapro) – and doing a few decision-making tasks. The purpose of the study is to understand how two chemicals in the brain, dopamine and serotonin, are involved in decision-making. This is not a form of …
 Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
18 years - 39 years
All genders
Phase 3
Interventional
The first purpose of this study is to test the safety of the addition of a drug called inotuzumab to the usual chemotherapy drugs used for adolescent young adults (ages 18-39). Inotuzumab is investigational and is not FDA-approved. Additionally,this study is to compare any good and bad effects of using …
 A Study of Venetoclax (ABT-199) in Combination with Liposomal Vincristine in Patients with Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia
18 years - 99 years
All genders
Phase 1
Interventional
This study is being done to determine what effects the therapy venetoclax has on acute lymphoblastic leukemia (ALL).This investigational therapy will be added to what is a standard, liposomal vincristine, to treat relapsed ALL.
 UPCC 04717: Phase I  open label  dose-escalation study to evaluate the safety  expansion  persistence of a single dose of UCART19 (allogeneic engineered T-cells expressing anti-CD19 chimeric antigen receptor)  administered intravenously in patients with relapsed or refractory CD19 positive B-cell acute lymphoblastic leukaemia (B-ALL)
99 years or below
All genders
Phase 1
The main aims of this study are to test the safety of up to 4 different doses of UCART19, and to identify the best dose of UCART19, by measuring what has happened to the leukemia cells at day 28 (28 days after the administration of UCART19), day 84 (84 days …
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