Found 126 Lymphocytic Leukemia, Acute trials
A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Prospective Multicenter Study of Transbronchial Microwave Ablation Using Robotic-Assisted Bronchoscopy in Subjects with Oligometastatic Tumors in the Lung
The primary objective of the study is to evaluate the safety and effectiveness of the NEUWAVETM FLEX MC Microwave Ablation System and Accessories used in transbronchial ablation procedures for adult subjects with oligometastatic tumors ( 2cm) in the lung. Technique Efficacy: Ablation of the target tumor(s) with the ablation zone …
A Study of the Safety and Efficacy of Pancreatic Endocrine Cell Clusters Implanted Into the Omentum of Type 1 Diabetes Patients With Severe Hypoglycemia (SUGR)
This study will evaluate the safety, efficacy and durability of SR-02 administered to the omentum of patients of Type 1 diabetes with severe recurrent hypoglycemia. The study will also help establish the optimal treatment dose. Although this study is open to patients with all HLA or blood types, immunosuppression to …
PRELIMINARY STUDY OF OPTICAL BIOMARKERS FOR NEURODEGENERATION IN CHRONIC CEREBROVASCULAR DISEASE
This research study will test whether a new optical device can reliably measure markers of blood flow and blood vessel function in the brain. We will be recruiting 60 subjects in total: 30 healthy, 15 with known narrowing of the carotid artery, and 15 small vessel stroke. All subjects will …
UPCC 21520: The LIMIT KRAS Mutant NSCLC Trial: Lysosome Inhibition to Enhance MAPK Inhibition Targeting KRAS Mutant NSCLC: A Phase 2 Open Label Trial of Binimetinib and Hydroxychloroquine in Patients with Advanced KRAS Mutant Non-Small Cell Lung Cancer
This study will evaluate using hydroxychloroquine (HCQ) along with binimetinib as an effective method for treating cancer. All patients will receive binimetinib at a standard dose approved for other cancers. The dose of HCQ will also be fixed based on ongoing phase I studies. Eligible subjects will have lung cancer …
A Phase 2 Randomized Open-Label Active Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of Islatravir in Combination with Lenacapavir in Virologically Suppressed People with HIV
This is a Phase 2, randomized, open-label, active-controlled, multicenter study to evaluate the safety, efficacy, and PK of ISL + LEN. The target population is virologically suppressed people living with HIV (PWH) who are at least 18 years of age and meet other study inclusion criteria. All participants will be …
BEAT-MS Multiple Sclerosis Trial
This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized at a 1 to 1 (1:1) ratio.All participants will be followed …
Evaluating Study Drug BI 1015550 over at least 52 weeks in patients with Progressive Fibrosing Interstitial Lung Diseases (PF-ILDs)
This study is being done to test the safety, effectiveness, and side effects of 2 different doses of the study drug, BI 1015550, when compared to taking a placebo, in subjects with PF-ILD. In this study you will either get the active study drug, BI 1015550 or a placebo. If …
Assessing Diagnostic Predictors of Airway Collapse in patients with Obstructive Sleep Apnea
This study is a multicenter study of up to 300 subjects diagnosed with OSA who are being evaluated for airway surgery, including hypoglossal nerve stimulation. Subjects will undergo standard evaluation for airway surgery as part of standard of care. In addition, a simple, non-invasive measurement of the pharyngeal width (PW) …
Polysomnography Validation of the Sansa Device
The purpose is to validate the Huxley Sansa device and automated scoring algorithm for detecting SDB events compared to the reference standard in-lab PSG. Participants will be recruited from Penn patients age 18+. This is a multi-site, sponsored study where Penn will rely on a central IRB, with enrollment across …
Assessment of T4032 (unpreserved bimatoprost 0.01%) versus Lumigan 0.01% in ocular hypertensive or glaucomatous patients
The purpose of this study is to find out about the safety and efficacy of T4032, which is a preservative-free formulation of bimatoprost (0.01%) for the treatment of glaucoma or ocular (eye) hypertension. There will be 5 to 6 study visits and participation will last up to 12 weeks (120 …
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