Found 114 Lymphocytic Leukemia, Acute trials
A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Requesting a reliance agreement with an external IRB. Study to evaluate pharmacokinetics, safety/tolerability, and immunogenicicty of ocrelizumab admistered subcutaneously in patients with MS. Pre-treated patients will be randomized (1:1) to dose-escalated, subcutaneous or IV administration. Treatment naive patients receive dose-escalated, subcutaneous administration only. All participants may then enter a dose …
The primary objective of the study is to evaluate the safety and effectiveness of the NEUWAVETM FLEX MC Microwave Ablation System and Accessories used in transbronchial ablation procedures for adult subjects with oligometastatic tumors ( 2cm) in the lung. Technique Efficacy: Ablation of the target tumor(s) with the ablation zone …
This is a Phase 2, randomized, open-label, active-controlled, multicenter study to evaluate the safety, efficacy, and PK of ISL + LEN. The target population is virologically suppressed people living with HIV (PWH) who are at least 18 years of age and meet other study inclusion criteria. All participants will be …
This study will evaluate using hydroxychloroquine (HCQ) along with binimetinib as an effective method for treating cancer. All patients will receive binimetinib at a standard dose approved for other cancers. The dose of HCQ will also be fixed based on ongoing phase I studies. Eligible subjects will have lung cancer …
This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized at a 1 to 1 (1:1) ratio.All participants will be followed …
This study is a multicenter study of up to 300 subjects diagnosed with OSA who are being evaluated for airway surgery, including hypoglossal nerve stimulation. Subjects will undergo standard evaluation for airway surgery as part of standard of care. In addition, a simple, non-invasive measurement of the pharyngeal width (PW) …
The purpose is to validate the Huxley Sansa device and automated scoring algorithm for detecting SDB events compared to the reference standard in-lab PSG. Participants will be recruited from Penn patients age 18+. This is a multi-site, sponsored study where Penn will rely on a central IRB, with enrollment across …
This study is being done to test the safety, effectiveness, and side effects of 2 different doses of the study drug, BI 1015550, when compared to taking a placebo, in subjects with PF-ILD. In this study you will either get the active study drug, BI 1015550 or a placebo. If …
The purpose of this study is to find out about the safety and efficacy of T4032, which is a preservative-free formulation of bimatoprost (0.01%) for the treatment of glaucoma or ocular (eye) hypertension. There will be 5 to 6 study visits and participation will last up to 12 weeks (120 …
This is a Phase 3 study of rozanolixizumab in anti-AChR or anti-MuSK autoantibody-positive patients with generalized MG who experience moderate to severe symptoms and are being considered for treatment with IVIg or PEX. The primary objective of the study is to demonstrate the clinical efficacy of rozanolixizumab in patients with …
