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Found 126 Lymphocytic Leukemia, Acute trials

A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study Evaluating Maternal and FetaL Outcomes in the ERA of ModulatorS (MAYFLOWERS)

18 years - 50 years
Female
The purpose of any research study is to answer questions. The MAYFLOWERS study is being done to look at how pregnancy affects the health of women with cystic fibrosis (CF) and to look at the health of babies born to women with CF. It is expected that most but not …

Efficacy and Safety of GL0034 in Overweight or Obese Adults With Type II Diabetes Mellitus

All genders
Phase 2
Interventional
This is a phase II, randomized, double-blind, placebo-controlled study to evaluate the efficacy and tolerability of GL0034 among type II diabetes mellitus subjects who are obese or overweight with weight-related comorbidities. Subjects will be put on either one of the four treatment arms (GL0034, once a week, subcutaneous injection) or …
 MG0003  A Phase 3  Randomized  Double-Blind  Placebo-Controlled Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Patients with Generalized Myasthenia Gravis

MG0003 A Phase 3 Randomized Double-Blind Placebo-Controlled Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Patients with Generalized Myasthenia Gravis

18 years - 99 years
All genders
Phase 3
This is a Phase 3 study of rozanolixizumab in anti-AChR or anti-MuSK autoantibody-positive patients with generalized MG who experience moderate to severe symptoms and are being considered for treatment with IVIg or PEX. The primary objective of the study is to demonstrate the clinical efficacy of rozanolixizumab in patients with …

Study to Evaluate drug GS-8588 in People With HIV-1 Who are Virologically Suppressed on Antiretroviral Therapy

18 years - 99 years
All genders
Phase 1
Interventional
The research study is being conducted to test an experimental drug, GS-8588, for the treatment and remission of human immunodeficiency virus (HIV) infection. GS-8588 is a special type of protein, called an antibody, that helps the immune system bring your immune cells closer to the cells infected with HIV. Finding …
 A5369: HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) as Therapeutic Vaccination in HIV-Infected Persons with Viral Suppression on Antiretroviral Therapy

A5369: HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) as Therapeutic Vaccination in HIV-Infected Persons with Viral Suppression on Antiretroviral Therapy

All genders
Phase 1
A5369 is a phase I/IIa, randomized, double-blind, placebo-controlled study to evaluate the safety, immunogenicity, and efficacy of p24CE/full-length Gag DNA, as a therapeutic vaccine in HIV-1 infected persons. The study targets to enroll 40 participants. All participants are well-suppressed on ART, current CD4 T cell counts greater than 500 cells/mm3, …
 Spironolactone for Regulating Blood Pressure after Intracerebral Hemorrhage

Spironolactone for Regulating Blood Pressure after Intracerebral Hemorrhage

18 years - 99 years
All genders
Blood pressure treatment is important for all survivors of intracerebral hemorrhage (ICH). High blood pressure after ICH puts patients at high risk for future strokes and memory problems. Nearly all doctors agree that patients  who have had a brain hemorrhage should be treated with blood pressure medications. But doctors are …
 Propranolol Rescue of Prolonged Labor

Propranolol Rescue of Prolonged Labor

18 years - 99 years
All genders
Phase 4
Over 30% of all cesarean deliveries (CD) performed in the United States are for prolonged labor. Current management strategies to resolve prolonged labor fail up to 50% of the time. The uterus is known to express beta receptors, which when stimulated, cause uterine relaxation. Accordingly, beta blockade has been shown …

A Phase 1/2 Randomized Double-Blind Placebo-Controlled Combined Single and Multiple Ascending Dose Study Evaluating the Safety Tolerability and Biological Activity of MRT5005 (COhCFTR mRNA/ICE LNP) Administered by Nebulization to Adult Subjects with Cystic Fibrosis

All genders
Phase 1
This research study is being done to study a new way to possibly treat cystic fibrosis lung disease. The investigational drug to be tested in the present study is known by its code name MRT5005. MRT5005 consists of very small particles containing messenger ribonucleic acid (mRNA), which has the genetic …

ARTFL LEFFTDS Longitudinal Frontotemporal Dementia Study (ALLFTD)

30 years - 99 years
All genders
Observational
The purpose of this study (ALLFTD) is to understand how Frontotemporal Lobar Degeneration (FTLD) syndromes progress over time, and to develop new tools to help with diagnosis and eventual treatment. The study is enrolling patients with FTLD syndromes. Additionally, the study is enrolling healthy members of families where there is …

Effect of Dapagliflozin on Submaximal Exercise Tolerance in Heart Failure

18 years - 99 years
All genders
The primary purpose of this study is to test whether the dapagliflozin (Dapa) will improve exercise duration in people with Heart Failure (HF). In HF, patients are limited in their ability to do all the things they want to do, and exercise as much as they would like, due to …
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