A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This research study is being conducted to collect information on those who have been diagnosed with a disease related to a heart valve dysfunction or abnormality, needing surgical repair, or replacement of the affected valve. This research study is collecting information about the disease and the treatment. Participants will be …
Patients greater than 18 years of age undergoing a neurosurgical procedure at Penn Medicine will be approached for enrollment. Currently, this study is open only at the HUP and Penn Presbyterian Medical Center locations.Current research suggests that severe bodily stress caused by surgery may impair the immune system's ability to …
The goal of this study is to improve the reliability of acquiring open-set speech recognition following ABI placement for retrocochlear deafness, to evaluate whether state of consciousness influences speech-based ABR. The researchers hypothesize that: 1) It will be possible to elicit speech-based ABR from surgically anesthetized patients. 2) Surgically anesthetized …
This is a prospective, multicenter, multi-cohort (limb and torso), non-randomized study designed to evaluate the safety and tolerability of the Humacyte HAV in vascular trauma patients undergoing surgery for vascular replacement or reconstruction. The University of Pennsylvania will participate as a site by enrolling subjects between the ages of 18 …
This study is being done to determine how well the study drug, BGB-290, gets into the brain tumor and to confirm if we can continuously and safely give BGB-290 and temozolomide as a combination treatment after surgery. We are testing a dose of temozolomide once a day combined with the …
Mixed urinary incontinence (MUI), defined as the presence of both stress urinary incontinence and urgency urinary incontinence, is a challenging condition for which clinicians frequently use multiple sequential treatments that have undergone limited head to head comparison in rigorous clinical trials. Mid-urethral Sling vs. Botox A (MUSA) is a randomized …
The overall prevalence of Ovarian Cancer in the United States according to the US SEER Registry is 182,710 women. Ovarian cancer also has the highest mortality rate of the gynecological cancers. The overall five-year survival rate is 45% and for Stages III and IV it is only 20-25%. The majority …
This study will gather real-world information on the post-market performance, and confirm safety and effectiveness of the CentriMag Circulatory Support System for patients surviving up 30 days post support or to hospital discharge, and for subjects who do not recover and are bridged to a heart transplant or long-term assist …
This project aims to create a national cohort of COVID-19 ICU survivors, quantify the longer-term burden of COVID-19 infection and treatment on laryngeal function, voice, communication and quality of life within the cohort and identify potential intervention targets to prevent post-intubation laryngeal injuries. Subjects will be recruited from Penn's Otorhinolaryngology …
The purpose of this research study is to collect blood samples and applicable medical history from subjects diagnosed with hereditary colon cancer syndromes like FAP, Lynch Syndrome and MYK-associated polyposis and their family members. These samples will be used to evaluate the ability of a blood test to provide early …