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Found 112 Surgery trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Study Evaluating Participants who Received CanGaroo  Envelope  Tyrx Envelope  or No Envelope During CIED Implantation
18 years - 99 years
All genders
People who have had surgery to implant a medical device that helps their heart may have had their surgery done in slightly different ways. In this study, the investigators are looking for people to participate who need to undergo another surgical procedure to change or revise their implanted heart device. …
 SOROCk- NRG-CC008 A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-Oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers
35 years - 50 years
Female
The main purpose of this study is to determine if two surgical procedures, the usual approach of removing the fallopian tubes and ovaries and the other approach of removing the fallopian tubes at this time with the plan to remove the ovaries at a later time, are no different for …
 To Serenade or To Sedate? That is Still The Question - A Followup Trial On Anxiolytic Options Before Peripheral Nerve Blocks
99 years or below
All genders
The research study is being conducted to determine if there are differences in anxiety scores, heart rate, blood pressure, and oxygen status when using sedation medication versus the patient's choice of listening to music while undergoing a peripheral nerve block before his or her surgery. The patient will either receive …
99 years or below
All genders
Phase 2
Subjects with Stage III resectable melanoma will receive adjuvant therapy, nivolumab or ipilimumab plus nivolumab, based on whether a pathologic complete response (CR) or near CR (less than 10% viable tumor cells) is achieved with one dose of nivolumab in the neoadjuvant setting followed by surgery.
18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this research study is to learn if the investigational study drug, pegsitacianine, helps in seeing the primary lung cancer tumor and identifying any additional cancerous tissue present in the lung for removal at the time of standard of care cancer surgery. Each participant will receive a single …
 Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)  A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
99 years or below
All genders
Phase 3
The purpose of this study is to find if adding the study drug, nivolumab (also known as OPVIDO), will limit lung cancer from growing back in patients with early stage non-small cell lung cancer. Nivolumab is a drug that may turn on the body's immune system to attack any cancer …
 Innovative Combination Immunotherapy for Metastatic Triple Negative Breast Cancer (TNBC)
18 years - 99 years
Female
Phase 2
This phase II trial studies how well avelumab in combination with binimetinib, utomilumab, or anti-OX40 antibody PF-04518600 works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like …
 Evaluation of Corneal Confocal Microscopy in Ocular Surface Disease and/or Neuropathic Pain Patients
99 years or below
All genders
The purpose of this study is two-fold. Since there is currently no FDA approved software to analyze these images, the images taken will be used to help improve and refine current software, or help develop new software, in the hopes that it will be approved by the FDA. The images …
 EA2174: A Phase II/III Study of Peri-operative Nivolumab and Ipilimumab in Patients with Locoregional Esophageal and Gastroesophageal Junction Adenocarcinoma
18 years - 99 years
All genders
Phase 3
This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. This trial is open to Penn Medicine's Abramson Cancer Center patients only. Please contact the …
99 years or below
All genders
This post-market, prospective, interventional, global, multi-center, randomized, nonblinded, dual-arm, clinical trial study will generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft System versus Gore Excluder/Excluder Conformable AAA Endoprosthesis in subjects with Abdominal Aortic Aneurysm (AAA). The primary objective is to evaluate sac regression outcomes in …