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Found 116 Surgery trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Intraoperative molecular imaging of pulmonary nodules by BY SGM-101

Intraoperative molecular imaging of pulmonary nodules by BY SGM-101

18 years - 99 years
All genders
Phase 1
Normal 0 false false false EN-US X-NONE X-NONE The research study is being conducted to determine if a new type of contrast agent can detect your cancer cells and to determine if the cancer has spread.  The dye is unique for the following reasons: ·      It is not radioactive ·      …
 PennRad BioBank

PennRad BioBank

18 years - 99 years
Female
800x600 Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Normal 0 false false false EN-US X-NONE X-NONE The goal of this study is to collect tissue and/or blood that may be used to identify gene, protein and enzyme markers that will predict cells’ response to breast cancer treatment. Tissue …

Cancer31 non cancer (1243)

18 years - 82 years
Female
Observational
500 patients will be prospectively recruited to undergo a fast breast MRI examination. The women will be recruited for the study will meet the following criteria: 1. status post primary breast cancer treated with breast conservation therapy 3 years prior to recruitment 2. negative DBT examination six months prior to …

Study to evaluate SAF312 eye drops in the treatment of post-operative corneal induced chronic pain (CICP) following Photorefractive Keratectomy (PRK) or Laser-assisted in Situ Keratomileusis (LASIK) surgeries

All genders
Many patients suffer from acute ocular pain due to different problems, however there is no available treatment for chronic eye pain (long lasting eye pain). Very often eye pain is reported after surgical procedures, like PRK and LASIK. Up to 60% of patients continue to have chronic pain beyond one …
 A  study of near infrared imaging of myocardial scar and epicardial ganglionated plexus in patients undergoing cardiac surgery

A study of near infrared imaging of myocardial scar and epicardial ganglionated plexus in patients undergoing cardiac surgery

18 years - 99 years
All genders
Observational
To determine the feasibility of near infrared (NIR) imaging of myocardial scar and epicardial adipose tissue in patients undergoing cardiac surgery.
 Treatment In Thoracic Aortic Aneurysm: Surgery versus Surveillance

Treatment In Thoracic Aortic Aneurysm: Surgery versus Surveillance

18 years - 79 years
All genders
This study aims to compare the outcomes of patients undergoing early surgical intervention for ascending aortic aneurysms to those undergoing aneurysm surveillance. Patients with aneurysm diameters between 5.0 and 5.4 cm will be randomized to receive either medical therapy or elective surgery and will be followed annually for 5 years. …

Intraoperative electrophysiological recording in patients undergoing brain surgery

All genders
The purpose of this protocol is to allow for intraoperative electrophysiological recording from patients already scheduled to undergo a craniotomy that will expose the cerebral cortex. During surgery, a recording array will be briefly placed on the surface of the brain and signals will be recorded while the patient is …
 Testing novel drugs or drug combinations to treat breast cancer before surgery

Testing novel drugs or drug combinations to treat breast cancer before surgery

18 years - 99 years
Female
A clinical trial to determine whether adding experimental agents to standard neoadjuvant paclitaxel (with or without trastuzumab), anthracycline, nad cyclosphosphamide increases the probability of pathologic complete response (pCR) over standard neoadjuvant chemotherapy for each biomarker signature established at trial entry, and to determine for each experimental agent used, the predictive …
 Bupivacaine RCT- Bupivacaine as Adjuvant for Post-operative Pain in Mohs micrographic surgery

Bupivacaine RCT- Bupivacaine as Adjuvant for Post-operative Pain in Mohs micrographic surgery

18 years - 99 years
All genders
The research study is being conducted to find the best ways to reduce pain after Mohs surgery. The research team hopes to learn if adding additional numbing medication at the end of surgery will help reduce pain afterwards. Penn Medicine patients having Mohs surgery will be invited to participate in …

ALM-488 for Intra-Operative Visualization of Nerves in Head and Neck Surgery

18 years - 99 years
All genders
The purpose of this study is to assess the safety of ALM-488, and to learn how well it shows nerve tissue in the body.