Found 110 medicine trials
A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The goal of this trial is to evaluate the safety of autologous genetically modified TC-110 T cells in adult patients with aggressive NHL (DLBCL, PMBCL, TFL, MCL), high-risk indolent NHL, or ALL. And to establish the recommended phase 2 dose (RP2D) for the NHL and ALL indications according to the …
This study will focus on fat buildup inside the heart muscle, a newly recognized factor that makes patients vulnerable to such fast heart rates, or ventricular tachycardia, after a heart attack. This work may identify more successful strategies for curing dangerously fast heart rates. Adult subjects with prior history of …
The target population are patients at Penn Medicine undergoing elective bariatric surgery; and are additionally participating in POW-R study ( Protocol #843280) Patients will be recruited to undergo liver wedge and visceral adipose tissue biopsy and provide blood samples. Liver samples will be processed for RNA, metabolomics, and biochemical and …
This post-approval study will collect safety, performance, effectiveness, and neck dilatation data on Alto Abdominal Stent Graft System for the endovascular treatment of infrarenal abdominal aortic aneurysms and evaluate real-world outcomes in comparison to commercially available comparator devices. Penn Medicine patients with the Alto Abdominal Stent Graft System, a device …
The purpose of this study is to see how safe the study medicine, IGV-001 plus standard of care (SOC), is and to compare IGV-001 with placebo (only standard of care) to see if it works in slowing GBM tumor regrowth. Participants for this study will be recruited from the patient …
HOPE is a randomized clinical trial that will evaluate approaches to reducing pain and opioid use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage renal disease. The hypothesis is that pain coping skills training will be effective at reducing pain and opioid use, and that buprenorphine …
Patients will be recruited from within the Penn Medicine Abramson Cancer Center pool of patients. This sub-study is part of a larger research study that is testing experimental treatments for melanoma. This sub-study is testing experimental drugs when they are given before and/or after melanoma surgery. Subjects will be assigned …
This clinical study will be a multi-center, open label, prospective study of 8 weeks of treatment with 24 weeks of follow-up to evaluate the safety and efficacy of OXERVATE 0.002% (20 mcg/mL) cenegermin-bkbj ophthalmic solution administered as one drop in the affected eye(s), 6 times per day at 2-hour intervals, …
This research study only enrolls hospitalized patients at Penn Medicine. The purpose of the study is to assess differences in respiratory and ventilation parameters between HFNC and helmet CPAP in obese patients with COVID-19 AHRF. We will enroll patients admitted to a HUP ICU with COVID-19 who have an obese …
This phase II/III trial compares the effect of adding chemotherapy before and after surgery versus after surgery alone (usual treatment) in treating patients with stage II-III gallbladder cancer. This study will determine whether giving chemotherapy before surgery increases the length of time before the cancer may return and whether it …
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