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Found 105 medicine trials

A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years or below
All genders
Phase 1
This study recruits participants directly from Penn Medicine clinics, during time of their clinical biopsies. Up to 40 participants with known or suspected primary or metastatic breast cancer who meet eligibility requirements for this study will undergo FTT PET/CT study imaging. Each PET/CT scan will include an injection of up …
 FS-CAMP: Fed-State Cardiac Arteriovenous Metabolomic Profiling
18 years - 99 years
All genders
This study will enroll subjects who are coming in for a clinical EP procedure that involves the use of venous, coronary sinus, and arterial line placement. Our patient population is primarily from the surrounding urban and suburban region of Penn Medicine.  The research team plans to quantify cardiac metabolism during …
 Duration and Nature of Long-Term Immunosuppression After Neurosurgical Procedure
18 years - 99 years
All genders
Patients greater than 18 years of age undergoing a neurosurgical procedure at Penn Medicine will be approached for enrollment. Currently, this study is open only at the HUP and Penn Presbyterian Medical Center locations.Current research suggests that severe bodily stress caused by surgery may impair the immune system's ability to …
18 years - 85 years
All genders
Interventional
The purpose of this study is to see if a test medicine not yet approved for market, named Rifaximin SSD-40IR given Twice Daily, will help to delay the first episode of overt hepatic encephalopathy (OHE) requiring hospitalization, in patients with liver cirrhosis and how safe it is to use in …
 Quality Improvement Assessment for Patient-Centered Community Health Worker Intervention
18 years - 99 years
All genders
The purpose of the IMPaCT Transitions program is to help low-income general medicine patients who have been cared for at the Hospital of the University of Pennsylvania or Presbyterian Hospital with the transition from hospital to a primary care clinic. The purpose of IMPaCT Home is to help low-SES patients …
 Phase 3  open label  single arm study to evaluate efficacy and safety of FIX gene transfer with PF-06838435 (rAAV Spark100-hFIX-Padua) in adult male participants with moderately severe to severe hemophilia B (FIX:C= or -2%) (BeneGene-2)
99 years or below
All genders
Phase 3
The research study is being conducted to test the safety and effectiveness of the study drug which is a gene therapy based treatment. Researchers want to see if the drug works to prevent the bleeding episodes commonly experienced by patient with Hemophilia B and to advance science and medicine. Subjects …
 Non-Dipping Hypertension and The Human Chronobiome
18 years - 99 years
All genders
Phase 1
Interventional
Do you have high nighttime blood pressure? Are you healthy, but interested in having a blood pressure study? Penn Medicine is seeking study participants 18years of age and older to have their blood pressure, physical activity, mobility, heart health, and social behavior monitored over 24 hours on two occasions. This …
 Inhaled AR-501 in Adults with P. Aeruginosa Infected Cystic Fibrosis Subjects
18 years - 49 years
All genders
Phase 1
This is a study of AR-501 (gallium citrate) solution, administered via inhalation, in adults with P. aeruginosa infected cystic fibrosis (CF). The study will evaluate the safety and pharmacokinetic (PK) and efficacy of repeat administrations of inhaled AR-501 solution in P. aeruginosa infected CF.
 Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis (RheSolve)
35 years - 99 years
All genders
Interventional
Prospective, randomized, parallel group, double-blind, concurrently controlled, multi-center clinical trial following patients to 2 years to assess the safety and effectiveness the treatment of the symptoms of chronic bronchitis in adult COPD patients with moderate to severe chronic bronchitis.
 Study of Daratumumab with Dose-Adjusted EPOCH in Newly Diagnosed Plasmablastic Lymphoma
18 years - 99 years
All genders
Patients with plasmablastic lymphoma are potential participants of this research trial. Patients with a type of B-cell non-Hodgkin lymphoma (NHL) will be invited from Penn Medicine practices. This research study is designed to test the safety of daratumumab, a drug added to the standard lymphoma treatment when given to individuals …