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Found 110 medicine trials

A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Phase 3 Multicenter Study of Gleolan (Aminolevulinic Acid Hydrochloride) to Enhance Visualization of Tumor in Patients with Newly Diagnosed or Recurrent Meningiomas
18 years - 99 years
All genders
Phase 3
This study is designed to investigate the safety, diagnostic performance, and clinical usefulness of Gleolan for the real time detection and visualization of meningiomas during tumor resection surgery. Potential patients who sign informed consent will be screened for eligibility before receiving an oral solution of Gleolan 3 hours prior to …
 A Clinical Study Evaluating the data Utility and Usability of Invu on pregnant subjects during virtual survaliance sessions  of Fetal and Maternal  heart rates and blood pressure readings
99 years or below
All genders
The purpose of this study is to determine whether tracing data (maternal and fetal heart rate) collected remotely on the Nuvo Invu device can be used for clinical management of pregnant patients. We will be recruiting generally healthy pregnant women with singleton gestations who at at least 32 weeks gestation …
 CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
18 years - 99 years
All genders
Phase 3
Interventional
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number of people with large hemispheric infarction (LHI). These studies suggested that the study drug was safe, did not cause serious side effects or discomfort, and …
99 years or below
All genders
Phase 1
This study recruits participants directly from Penn Medicine clinics, during time of their clinical biopsies. Up to 40 participants with known or suspected primary or metastatic breast cancer who meet eligibility requirements for this study will undergo FTT PET/CT study imaging. Each PET/CT scan will include an injection of up …
 Duration and Nature of Long-Term Immunosuppression After Neurosurgical Procedure
18 years - 99 years
All genders
Patients greater than 18 years of age undergoing a neurosurgical procedure at Penn Medicine will be approached for enrollment. Currently, this study is open only at the HUP and Penn Presbyterian Medical Center locations.Current research suggests that severe bodily stress caused by surgery may impair the immune system's ability to …
 Quality Improvement Assessment for Patient-Centered Community Health Worker Intervention
18 years - 99 years
All genders
The purpose of the IMPaCT Transitions program is to help low-income general medicine patients who have been cared for at the Hospital of the University of Pennsylvania or Presbyterian Hospital with the transition from hospital to a primary care clinic. The purpose of IMPaCT Home is to help low-SES patients …
 A Clinical Trial to Evaluate the Safety and Efficacy of Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor
99 years or below
All genders
The Exablate Model 4000 Type-1.0/1.1 Neuro system involves using an advanced, non-invasive technique currently approved by the Food and Drug Administration (FDA) to treat one side of your brain in a procedure called a thalamotomy (lesion the thalamus). This procedure involves performing an ablation (lesion) of an area of the …
 ASPEN- A Phase 3  Randomized  Double-Blind  Placebo-Controlled Study to Assess the Efficacy  Safety  and Tolerability of Brensocatib Administered Once Daily for 52 Weeks in Subjects With Non-Cystic Fibrosis Bronchiectasis
18 years - 85 years
All genders
Phase 3
Interventional
Penn Medicine patients already participating in protocol INS1007 301 will be invited to participate in this study. The Pharmacokinetic (PK) portion of this substudy is designed to evaluate the amount of brensocatib present in your blood at certain time periods before and after the study drug is administered, and the …
 Phase 3  open label  single arm study to evaluate efficacy and safety of FIX gene transfer with PF-06838435 (rAAV Spark100-hFIX-Padua) in adult male participants with moderately severe to severe hemophilia B (FIX:C= or -2%) (BeneGene-2)
99 years or below
All genders
Phase 3
The research study is being conducted to test the safety and effectiveness of the study drug which is a gene therapy based treatment. Researchers want to see if the drug works to prevent the bleeding episodes commonly experienced by patient with Hemophilia B and to advance science and medicine. Subjects …
 A Randomized study of EHR Defaults and Using social Comparison feedback to Effectively decrease opioid prescription pill burden - The REDUCE Trial
99 years or below
All genders
Observational
Opioid-related abuse and overdose represent a growing national epidemic in the United States. Clinician practice patterns play an important role: opioid prescriptions impact the likelihood that patients will misuse or become dependent on these medications, with longer prescriptions leading to greater sustained use. In this study, we will evaluate a …