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Found 110 medicine trials

A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 ONC201 in recurrent high-grade glioma
18 years - 99 years
All genders
Phase 2
This is a phase II, open-label study of ONC201 in adults with recurrent high- grade glioma. Subjects for this study will be recruited from the patient population that present to the Penn Brain tumor center- Department of Neurosurgery or Department of Medicine division of Hematology/ Oncology for evaluation and treatment …
 A Randomized Study to Compare Efficacy  Safety  and Tolerability of Macitentan 75mg Versus Macitentan 10mg in Patients with Pulmonary Arterial Hypertension  Followed by an Open-label Treatment Period with Macitentan 75mg
18 years - 75 years
All genders
Phase 3
TThe research study is being conducted to compare macitentan 75 mg with the approved macitentan 10 mg to see if it is well tolerated, safe and useful for treating patients with pulmonary arterial hypertension (PAH).
 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis
40 years - 99 years
All genders
This study is looking to see if inhaled treprostinil helps patients with IPF improve their pulmonary function tests. Patients will randomized to either placebo or inhaled treprostinil and will also undergo the following throughout the study: PFTs, physical exams, EKGs, HRCT, questionnaires, vital signs, lab tests
 FLowRetriever for Acute Massive Pulmonary Embolism
18 years - 99 years
All genders
Observational
To evaluate treatment outcomes of patients diagnosed with high-risk (massive) pulmonary embolism
 Inhaled AR-501 in Adults with P. Aeruginosa Infected Cystic Fibrosis Subjects
18 years - 49 years
All genders
Phase 1
This is a study of AR-501 (gallium citrate) solution, administered via inhalation, in adults with P. aeruginosa infected cystic fibrosis (CF). The study will evaluate the safety and pharmacokinetic (PK) and efficacy of repeat administrations of inhaled AR-501 solution in P. aeruginosa infected CF.
 Transbronchial Biopsy Assisted by Robot Guidance in the Evaluation of Tumors of the Lung (TARGET)
21 years - 99 years
All genders
Observational
This study is designed to evaluate clinical safety and diagnostic accuracy of the robotic-assisted bronchoscopy with biopsy performed with the Monarch™ Endoscopy Platform in a broad range of patients with pulmonary lesions.
 Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis (RheSolve)
35 years - 99 years
All genders
Interventional
Prospective, randomized, parallel group, double-blind, concurrently controlled, multi-center clinical trial following patients to 2 years to assess the safety and effectiveness the treatment of the symptoms of chronic bronchitis in adult COPD patients with moderate to severe chronic bronchitis.
 The FIRE Trial: Reducing patient memory recall in the burning mouth patient population
18 years - 99 years
All genders
Observational
The purpose of this study is to collect real-time data, such as pain symptoms and exercise habits, to investigate the factors that influence burning mouth symptoms. Participants will be asked to complete questionnaires during the in-person visits and you will receive up to three, random daily notifications from your smartphone …
 Exploratory Study of Mavacamten (MYK-461) in Patients with Symptomatic Non-obstructive Hypertrophic Cardiomyopathy (nHCM) and Preserved Left Ventricular Ejection Fraction
18 years - 99 years
All genders
Phase 2
The purpose of this study is to compare the effect of the investigational drug, mavacamten, (MYK-461), to a placebo (an inactive substance) in patients with Non-obstructive Hypertrophic Cardiomyopathy (nHCM).
99 years or below
All genders
This Post Approval Study is a multi-center, prospective, open label, single arm cohort study to evaluate the long-term safety, long-term effectiveness, and survival rate in subjects implanted with the remed System from the remed System Pivotal Trial. Up to 94 subjects will be enrolled at up to 21 sites in …
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