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Found 110 medicine trials

A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

“The Shift Worker’s Microbiome”

40 years - 59 years
Male
We are looking for healthy males, age 40-59 years old, non-smoking un-medicated who work the "shift-work" schedule (>3 shifts per month outside 7 am-6 pm for the past 10 or more years & own a smartphone which installs the remote sensing applications. or "day workers" who work 7 am-6 pm …
 Tobacco Product Advertising Study

Tobacco Product Advertising Study

21 years - 29 years
Accepts healthy volunteer
All genders
The University of Pennsylvania's Tobacco Use Research Center is recruiting young adults between the ages of 21-29 who use or have previously used cigarettes and other tobacco products for a research study evaluating reactions to tobacco product advertising. This is not a quit smoking study.

Pilot, Single Center, Feasibility Study of Cuirass Biphasic Ventilator in Chronic Obstructive Pulmonary Disease Patients

21 years - 79 years
All genders
Phase 1
The research study is being conducted to learn about the work of breathing support that an external breathing support device can provide compared to a person’s baseline ability. The research study is sponsored by RightAir Inc, the makers of the device being investigated, the AIR-AD cuirass ventilator. This study is …

Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial

18 years - 50 years
All genders
Interventional
COSMID is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. The goal of the COSMID trial is to answer the question: For patients with QoL-limiting diverticular disease, is elective colectomy more effective than best medical …
 Fusion - FPX-01-01

Fusion - FPX-01-01

18 years - 99 years
All genders
Phase 1
A first-in-man Phase 1, non-randomized, multi-centre, open-label clinical trial designed to investigate the safety, tolerability, pharmacokinetics of [111In]-FPI-1547 Injection and [225Ac]-FPI-1434 Injection and to establish the maximum tolerated dose of a single [225Ac]-FPI-1434 Injection in patients with solid tumours with demonstrated tumour uptake of [111In]-FPI-1547. Includes a sub-study of FPI-1175 …
 MG0003  A Phase 3  Randomized  Double-Blind  Placebo-Controlled Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Patients with Generalized Myasthenia Gravis

MG0003 A Phase 3 Randomized Double-Blind Placebo-Controlled Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Patients with Generalized Myasthenia Gravis

18 years - 99 years
All genders
Phase 3
This is a Phase 3 study of rozanolixizumab in anti-AChR or anti-MuSK autoantibody-positive patients with generalized MG who experience moderate to severe symptoms and are being considered for treatment with IVIg or PEX. The primary objective of the study is to demonstrate the clinical efficacy of rozanolixizumab in patients with …

Study to evaluate antibody response to an additional dose of COVID-19 vaccination with and without immunosuppression reduction in kidney and liver transplant recipients.

18 years - 99 years
All genders
The purpose of the study is to find out whether an extra dose of COVID-19 study dose of vaccine will help to protect people who have had a liver or kidney transplant from COVID-19 by causing their body to make antibodies against the virus that causes COVID-19. Many transplant recipients …
 FS-CAMP: Fed-State Cardiac Arteriovenous Metabolomic Profiling

FS-CAMP: Fed-State Cardiac Arteriovenous Metabolomic Profiling

18 years - 99 years
All genders
This study will enroll subjects who are coming in for a clinical EP procedure that involves the use of venous, coronary sinus, and arterial line placement. Our patient population is primarily from the surrounding urban and suburban region of Penn Medicine.  The research team plans to quantify cardiac metabolism during …

Study to Assess Rifaximin Soluble Solid Dispersion (Ssd) Tablets for the Delay of Encephalopathy Decompensation in Cirrhosis (Red-C)

18 years - 85 years
All genders
Interventional
The purpose of this study is to see if a test medicine not yet approved for market, named Rifaximin SSD-40IR given Twice Daily, will help to delay the first episode of overt hepatic encephalopathy (OHE) requiring hospitalization, in patients with liver cirrhosis and how safe it is to use in …
 Phase IV Open Label Study of the Effects of Secukinumab on Nail Psoriasis and non-invasive measures of enthesitis

Phase IV Open Label Study of the Effects of Secukinumab on Nail Psoriasis and non-invasive measures of enthesitis

18 years - 99 years
All genders
Phase 4
The purpose of this study is to determine how psoriatic nail disease is affected by secukinumab. Secukinumab (Cosentyx®) is a prescription medicine that has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of plaque psoriasis, active psoriatic arthritis, and active ankylosing spondylitis in adults. While …
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