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Found 40 Liver Disease trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years or below
All genders
Phase 2
A phase 2B, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of BMS-986036 in subjects with NASH and F3 fibrosis. The treatment period is 48 weeks, with drug administered as a once-weekly injection. There is also a follow-up period to assess long-term bone mineral density and immunogenicity. Target population …
 Prevention of Mortality with Long-Term Administration of Human Albumin in Subjects with Decompensated Cirrhosis and Ascites
99 years or below
All genders
Phase 3
This study is designed to evaluate the effects of Albutein 20% infusion on long-term survival (1-year transplant-free) in liver cirrhosis compared to the Standard Medical Treatment (SMT).
 A study evaluating the safety and efficacy of selective internal radiation therapy (SIRT) using SIR-Spheres® Y-90 resin microspheres on duration of response (DoR) and objective response rate (ORR) in hepatocellular carcinoma (HCC) patients (DOORwaY90 Study)
18 years - 99 years
All genders
Phase 1
Observational
The objective of this pivotal study is to evaluate the safety and effectiveness of SIRT using SIR-Spheres Y-90 resin microspheres as first-line treatment for local control of HCC (Barcelona clinic liver cancer (BCLC) stage A, BCLC stage B1 and BCLC stage B2).
99 years or below
All genders
Determine the reproducibility of the subharmonic aided pressure estimation (SHAPE) algorithm in subjects to estimate portal pressures with an ultrasound scanner. Examine if serial SHAPE can accurately predict development of ascites and other liver related events. Use SHAPE to monitor treatment response in patients identified with portal hypertension and compare …
16 years - 99 years
All genders
Interventional
Preeclampsia is a serious medical condition that can happen during pregnancy. It usually starts with increasing blood pressure and could affect liver, kidney or other organ functions. This study will to assess whether daily treatment with investigational drug pravastatin administered early in pregnancy reduces the rate of preeclampsia in high-risk …
 CAPRICORN-19
18 years - 99 years
All genders
In this study, the Investigators at the University of Pennsylvania will assess organ-specific biomarker profiles (proteins and metabolites), in order to better understand biologic processes, the interplay between the heart and extracardiac organs, and their role in human disease, with an emphasis on cardiovascular disease. The study will specifically focus …
18 years - 99 years
All genders
The primary purpose of this study is to test whether the dapagliflozin (Dapa) will improve exercise duration in people with Heart Failure (HF). In HF, patients are limited in their ability to do all the things they want to do, and exercise as much as they would like, due to …
 Phase 2 Trial of AGEN2034 (anti-PD-1) as a Monotherapy of Combination Therapy with AGEN1884 (anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer (Second Line) - RaPiDS
99 years or below
All genders
Phase 2
The research study is being conducted to study the PD-1 antibody, AGEN2034 alone, or in combination with the CTLA-4 antibody, AGEN1884, in women with recurrent cervical cancer. Subjects will be asked to complete the following research procedures: 12 lead electrocardiogram (ECG) and evaluation of heart function (to determine heart health). …
 Long Acting Therapy to Improve Treatment SUccess in Daily LifE (The LATITUDE Study)
18 years - 70 years
All genders
Phase 3
This study is meant for patients who have difficulty taking their HIV meds as prescribed.  One goal of the study is to test the effectiveness of long-acting antiretroviral therapy (ART) -- a once-a-month injection that replaces daily ART pills. You will also receive compensation for participating in this study, with …
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