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Found 39 Liver Disease trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Safety and Immunogenicity Study of SARS-CoV-2 mRNA-1273 Vaccine in Adult Solid Organ Transplant Recipients and Healthy Controls
18 years - 99 years
Accepts healthy volunteer
All genders
Phase 3
The research study is being conducted to study the effectiveness of the mRNA-1273 study vaccine in people who have received a kidney or liver transplant. Healthy participants are being included in the study to compare the results from these participants to those who have had a kidney or liver transplant. …
99 years or below
All genders
Determine the reproducibility of the subharmonic aided pressure estimation (SHAPE) algorithm in subjects to estimate portal pressures with an ultrasound scanner. Examine if serial SHAPE can accurately predict development of ascites and other liver related events. Use SHAPE to monitor treatment response in patients identified with portal hypertension and compare …
 A Study to Evaluate the Effectiveness and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis
18 years - 99 years
All genders
Phase 3
Interventional
AL (or light chain) amyloidosis begins in the bone marrow where abnormal proteins misfold and create free light chains that cannot be broken down. These free light chains bind together to form amyloid fibrils that build up in the extracellular space of organs, affecting the kidneys, heart, liver, spleen, nervous …
 Phase 2 Trial of AGEN2034 (anti-PD-1) as a Monotherapy of Combination Therapy with AGEN1884 (anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer (Second Line) - RaPiDS
99 years or below
All genders
Phase 2
The research study is being conducted to study the PD-1 antibody, AGEN2034 alone, or in combination with the CTLA-4 antibody, AGEN1884, in women with recurrent cervical cancer. Subjects will be asked to complete the following research procedures: 12 lead electrocardiogram (ECG) and evaluation of heart function (to determine heart health). …
 ANDROMEDA-SHOCK-2 Trial
18 years - 99 years
All genders
Septic shock is a disease of the circulatory system representing a complication of serious infections, and is associated with a very high mortality, since around 1/3 of patients with this condition die. This disease produces a series of alterations in the body, including failure of the heart, kidneys, liver, among …
99 years or below
All genders
The main purpose of this study is to see if study drug CAM2029 works and is safe for people with polycystic liver disease (PLD). The study will also look at: • How the study drug affects the body (“pharmacodynamics”) • What the body does to the study drug (“pharmacokinetics”). This is a Phase …
 Mixed Meal Tolerance Test and Cirrhosis Study
1 years - 75 years
All genders
This is a study of 12 subjects with cirrhosis. Blood is collected at CHPS for metabolomic analysis and MMTT. The meal consumed for MMTT will be a convenience-style breakfast. In addition to research testing on blood, urine, and stool, dietary recalls and the Penn Diet Survey will be conducted. The …
99 years or below
All genders
Phase 2
A phase 2B, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of BMS-986036 in subjects with NASH and compensated cirrhosis. The treatment period is 48 weeks, with drug administered as a once-weekly injection. There is also a follow-up period to assess long-term bone mineral density and immunogenicity. Target population …
18 years - 85 years
All genders
Interventional
The purpose of this study is to see if a test medicine not yet approved for market, named Rifaximin SSD-40IR given Twice Daily, will help to delay the first episode of overt hepatic encephalopathy (OHE) requiring hospitalization, in patients with liver cirrhosis and how safe it is to use in …
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