Found 582 Barrett's Esophagus trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Phase I Trial of GFR4 CART Cells in Adult Patients with Recurrent or Metastatic Medullary Thyroid Cancer
This is an open-label phase 1 study to assess the safety and feasibility of autologous T cells expressing a single-chain scFv targeting GFRa4 with tandem TCR/CD3 and 4-1BB (TCR/4-1BB) costimulatory domains (referred to as CART-GFRa4) in patients with incurable medullary thyroid cancer (MTC). This is a Phase 1 study evaluating …
Antithrombotic Strategies in Hospitalized Adults with COVID-19
The purpose of this study is to compare the effectiveness of antithrombotic strategies for prevention of adverse outcomes in COVID-19 positive inpatients. Doctors use anticoagulation medicines, known as “blood thinners”, to lower the risk of blood clots forming in blood vessels (veins and arteries). The chance of blood clots in …
Recovery-Oriented Cognitive Therapy for Families
The purpose of this study is to evaluate the therapeutic benefit for participants receiving Recovery-Oriented Cognitive Therapy (CT-R) for families- a cognitive therapy based group for family members of individuals in the early stages of psychosis. A CT-R based intervention has shown to be effective for individuals with psychosis, offers …
Adaptive Platform Treatment Trial for Outpatients with COVID-19 - ACTIV-2
The ACTIV-2 Study is testing an investigational medicine to see if they are safe and can help adults with COVID-19 get better.The type of investigational medicine you might receive in the study is a monoclonal antibody. Antibodies are naturally made by your body to help fight disease. Monoclonal antibodies are …
CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number of people with large hemispheric infarction (LHI). These studies suggested that the study drug was safe, did not cause serious side effects or discomfort, and …
Duration and Nature of Long-Term Immunosuppression After Neurosurgical Procedure
Patients greater than 18 years of age undergoing a neurosurgical procedure at Penn Medicine will be approached for enrollment. Currently, this study is open only at the HUP and Penn Presbyterian Medical Center locations.Current research suggests that severe bodily stress caused by surgery may impair the immune system's ability to …
Intramolecular Imaging with ICG (PRIME)
The purpose of this protocol is to monitor the rate of recurrence in patients who undergo cancer surgery. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove …
EC17 for Intraoperative Imaging in Occult Ovarian Cancer
The overall prevalence of Ovarian Cancer in the United States according to the US SEER Registry is 182,710 women. Ovarian cancer also has the highest mortality rate of the gynecological cancers. The overall five-year survival rate is 45% and for Stages III and IV it is only 20-25%. The majority …
Evaluation of In Vivo Neuroinflammation in Alzheimers Disease Using Novel Positron Emission Tomography (PET/CT) Imaging
PET/CT imaging will be used to evaluate neuroinflammation in subjects with Alzheimer's Disease and Healthy Controls, using the investigational radiotracers [11C]PBR28 and[18F]NOS. Each subject will have one PET/CT session that includes both [11C]PBR28 and [18F]NOS injections and scan of the brain performed sequentially. Subjects may also undergo a brain MRI …
A study assessing the efficacy and feasibility of virtual cardiac rehabilitation with remotely monitored exercise (VCR)
This will be an observational study to investigate the feasibility and efficacy of a home-based, tech enabled, remotely supervised, cardiac rehabilitation (CR) program in qualifying American adults who cannot participate in traditional center based rehab.This study aims to investigate the feasibility and effectiveness of Carda Healths remotely administered cardiac rehab …
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