Found 582 Barrett's Esophagus trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Phase 2 Trial Of All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition In Recurrent IDH-Mutant Glioma
The purpose of this research study will be to evaluate the safety and effectiveness of two investigational drugs, All-trans retinoic acid (ATRA) and Retifanlimab (anti-PD1 monoclonal antibody), in treating recurrent IDH-mutant gliomas. Objective radiographic response (CR + PR + MR) using Response Assessment in Neuro-Oncology (RANO) criteria by measurable disease …
Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients
Primary Objectives: 1. To establish the prevalence of neuropathic corneal pain in patients with ocular surface discomfort. 2. To assess the overlap of neuropathic corneal pain with dry eye disease in patients in diseases that are currently thought to be mutually exclusive. 3. To establish the prevalence of subtypes of …
Chronic insomnia and CSF markers of dementia - Phase 2
The longstanding view has been that insomnia, and other forms of sleep disturbance, emerge as a consequence of dementia and are the result of progressive neuronal damage. However, there is growing evidence that the direction of causation may go both ways, with sleep disturbance potentially increasing vulnerability to dementia. Longitudinal …
Detection of cell-free circulating tumor DNA in patients with glioblastma undergoing treatment with first-line chemoradiotherapy
Glioblastoma (GBM) is the most common primary brain tumor in adults and is uniformly fatal. During standard adjuvant treatment for GBM following initial surgical resection of the tumor, patients are treated with a combination of radiation and chemotherapy. During and after this adjuvant treatment, patients are monitored for disease progression …
Aging Chronobiome Study (Acronym-1)
We invite you to participate in a research study where we explore how young and old people differ in their behavioral and biological rhythms. The main criteria to qualify as a research subject are: 1.) you are apparent healthy, 2.) you own a smartphone and 3.) you are either between …
Trial to Optimize Patients Selection for Endovascular Treatment in Acute Ischemic Stroke
Stroke can occur when a clot stops the flow of the blood in one of the arteries supplying the brain. This type of stroke, called ischemic stroke, can be treated alone or in a combination of drugs to dissolve the clot, devices to remove the clot (mechanical thrombectomy) or use …
Testing Novel Pharmacogenetic and Adherence Optimization Treatments to Improve the Effectiveness of Smoking Cessation Treatments for Smokers with HIV
The research study is being conducted to examine the effects of personalized smoking cessation medication treatment in order to help people with HIV/AIDS to quit smoking. During the study, participants will take either varenicline (brand name Chantix®) or use the nicotine patch, and they will receive smoking cessation therapy with …
The STandard versus ImAging SuBstrate Aided Ablation in Severe Left VEntricular Dysfunction VT
PURPOSE: The overall purpose of the study is to assess the procedural safety profile and clinical efficacy outcomes of an imaging substrate-aided ventricular tachycardia (VT) ablation strategy that avoids general anesthesia, limits inductions, and reduces time devoted to substrate mapping in heart failure patients with severe left ventricular dysfunction. Primary …
Alzheimers Disease Neuroimaging Initiative 3 (ADNI3)
Since its launch in 2004, the overarching aim of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) has been realized in informing the design of therapeutic trials in AD. ADNI3 continues the previously funded ADNI1, ADNI-GO, and ADNI2 studies that have been combined public/private collaborations between academia and industry to determine the …
Harnessing Hormonal Variation to Probe Neural Mechanisms of OCD and Symptom Reduction by EX/RP
Studies show that hormones affect the brain’s fear extinction network, which is relevant for therapy involving exposure and ritual prevention (EX/RP), a first-line treatment for obsessive compulsive disorder (OCD). This study will examine the effect of delivering EX/RP to women during different phases in their menstrual cycle to determine the effects of hormones on the …
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