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Found 582 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Effect of Dapagliflozin on Submaximal Exercise Tolerance in Heart Failure

18 years - 99 years
All genders
The primary purpose of this study is to test whether the dapagliflozin (Dapa) will improve exercise duration in people with Heart Failure (HF). In HF, patients are limited in their ability to do all the things they want to do, and exercise as much as they would like, due to …

Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial

18 years - 50 years
All genders
Interventional
COSMID is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. The goal of the COSMID trial is to answer the question: For patients with QoL-limiting diverticular disease, is elective colectomy more effective than best medical …

Investigating Study Drug RO4786967 in Participants with Idopathic Parkinson's Disease.

18 years - 99 years
All genders
Interventional
Parkinson’s disease is a chronic disease of the nervous system that gets worse over time. Available treatments cannot stop or slow down the worsening over time. Some evidence suggests that people with Parkinson’s disease may have more inflammation in the brain. This is thought to be one of the reasons …

Functional and Structural Assessment of Endobronchial Valve Recipients Using Dynamic Hyperpolarized Xenon-129 MRI

18 years - 99 years
All genders
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 magnetic resonance imaging (MRI) in diagnosing and predicting treatment outcomes for patients who received endobronchial valve (EBV) therapy to treat chronic obstructive pulmonary disease (COPD). COPD is a disease of the lungs caused most often by …

Study to Investigate Drug BIIB132 Administered to Adults With Spinocerebellar Ataxia 3

18 years - 70 years
All genders
Phase 1
Interventional
The purpose of this research study is to learn more about a study drug that may affect patients with spinocerebellar ataxia type 3 (SCA3). This type of drug is called an antisense oligonucleotide. Eligible participants in this study will have the study drug injected into the fluid surrounding their spinal …

The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

18 years - 99 years
All genders
Observational
The purpose of the study is to learn more about the treatment outcomes for small renal masses. The study team wants to keep track of how people do after they have chosen surveillance or surgery to learn more about the natural progression of disease to better recognize and understand it. …

Trial to assess efficacy and safety of octreotide subcutaneous depot (CAM2029) in patients with symptomatic polycystic liver disease

All genders
The main purpose of this study is to see if study drug CAM2029 works and is safe for people with polycystic liver disease (PLD). The study will also look at: • How the study drug affects the body (“pharmacodynamics”) • What the body does to the study drug (“pharmacokinetics”). This is a Phase …

Physical Activity and Fibrosing Interstitial Lung Disease (AP-PID)

All genders
Interventional
Fibrotic interstitial lungs diseases (ILD) are a group of chronic and rare diseases characterized by an altered blood oxygenation in the lung, leading to dyspnea and physical limitation. Physical training is efficient to fight vicious circle of physical deconditioning observed in ILD. Eccentric cycling is an interesting modality of endurance …
 EVALUATION OF THE VALIANT MONA LSA THORACIC STENT GRAFT SYSTEM IN DESCENDING THORACIC AORTIC ANEURYSMS AND CHRONIC DISSECTIONS

EVALUATION OF THE VALIANT MONA LSA THORACIC STENT GRAFT SYSTEM IN DESCENDING THORACIC AORTIC ANEURYSMS AND CHRONIC DISSECTIONS

All genders
The trial involves an investigational device (not approved by the FDA) for subjects who have an aneurysm (bulge), dissection (tear) or a penetrating ulcer (bubble) of the descending aorta that involve an artery (main blood vessel in your body). The subject must need to have one of their blood vessels …

[18F]FLUOROPROPYL-TRIMETHOPRIM (F-TMP) PET/CT IMAGING TO EVALUATE BIODISTRIBUTION AND KINETICS IN HUMAN SUBJECTS

All genders
Phase 1
Patients with known or suspected bacterial infection at the time screening are eligible for this study. Patients may participate in this study if they are at least 18 years of age, and most participants will be receiving care at the clinical practices of the University of Pennsylvania. Up to 20 …
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