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Found 116 Surgery trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Study Evaluating Participants who Received CanGaroo  Envelope  Tyrx Envelope  or No Envelope During CIED Implantation

Study Evaluating Participants who Received CanGaroo Envelope Tyrx Envelope or No Envelope During CIED Implantation

18 years - 99 years
All genders
People who have had surgery to implant a medical device that helps their heart may have had their surgery done in slightly different ways. In this study, the investigators are looking for people to participate who need to undergo another surgical procedure to change or revise their implanted heart device. …
 Towards predicting the analgesic response to ibuprofen following third-molar extraction

Towards predicting the analgesic response to ibuprofen following third-molar extraction

18 years - 64 years
All genders
NSAIDs like ibuprofen are pain relievers that are commonly used to reduce pain after dental procedures.  Patients who have their impacted third molar teeth taken out usually experience pain one to three hours after surgery and require pain relievers for at least 2 days. Most people (about 70-90%) experience good …

NONINTERVENTIONAL EXTENSION STUDY FOR PATIENTS TREATED IN STUDY R5459-RT-1944 WITH REGN5459 OR REGN5458 (BCMA CD3 BISPECIFIC ANTIBODIES) WHO RECEIVE A KIDNEY TRANSPLANT

All genders
The primary objective of the study is to assess adverse events (AEs) and serious adverse events (SAEs) in kidney transplant recipients previously treated with REGN5459 or REGN5458 in the R5459-RT-1944 study. The primary endpoint for this study is the incidence of AEs and SAEs over a 12-month period, starting at …

A Prospective Observational Study of Outcomes from Proximal Thoracic Aortic Disease

All genders
The purpose of this registry is to collect real-time data for those patients who have aortic disease of their ascending (top) aorta and the aortic arch (curved area where the vessels that supply the brain with blood). The current treatment requires open surgery or a hybrid procedure (open surgery with …
 SOROCk- NRG-CC008 A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-Oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers

SOROCk- NRG-CC008 A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-Oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers

35 years - 50 years
Female
The main purpose of this study is to determine if two surgical procedures, the usual approach of removing the fallopian tubes and ovaries and the other approach of removing the fallopian tubes at this time with the plan to remove the ovaries at a later time, are no different for …
 To Serenade or To Sedate? That is Still The Question - A Followup Trial On Anxiolytic Options Before Peripheral Nerve Blocks

To Serenade or To Sedate? That is Still The Question - A Followup Trial On Anxiolytic Options Before Peripheral Nerve Blocks

All genders
The research study is being conducted to determine if there are differences in anxiety scores, heart rate, blood pressure, and oxygen status when using sedation medication versus the patient's choice of listening to music while undergoing a peripheral nerve block before his or her surgery. The patient will either receive …

Pilot Surgical PK Study of BGB324 in Recurrent Glioblastoma Patients

18 years - 99 years
All genders
Phase 1
Interventional
The purpose of this study is to test the ability of a new drug, BGB324, to get into the brain tumor (e.g.by crossing the blood brain barrier) in patients with recurrent glioblastoma who require surgery.

PREPARE: A Pragmatic Randomized trial Evaluating Pre-operative Alcohol skin solutions in FRactured Extremities

18 years - 99 years
All genders
Observational
The purpose of this study is to determine which pre-operative solution, iodine-povacrylex or chlorhexidine gluconate, is better at lowering the risk of infection and complications requiring additional surgery in patients with fractures.

The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

18 years - 99 years
All genders
Observational
The purpose of the study is to learn more about the treatment outcomes for small renal masses. The study team wants to keep track of how people do after they have chosen surveillance or surgery to learn more about the natural progression of disease to better recognize and understand it. …
 Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer

Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer

All genders
Phase 1
Surgery is the best treatment for patients with Stage I or II lung cancer; however, nearly 60% of patients have recurrence. Additional immunotherapeutic agents given before surgery may be greatly reduce recurrence. This is a Standard Phase I, 3+3 dose escalation trial designed to evaluate the safety and toxicity of …
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