Found 107 Muscular Dystrophy trials
A listing of Muscular Dystrophy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenic stroke
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Investigation of the Effect of Branched Chain Amino Acids on Fat-Induced Insulin Resistance in Healthy Adults.
Elevations in plasma levels of branched chain amino acids (BCAAs, comprising leucine, valine, and isoleucine), a large component of protein, are strongly associated with insulin resistance and type 2 diabetes, but mechanisms for this relationship are unclear. This protocol will determine whether excess BCAAs worsen free fatty acid-induced insulin resistance. …
Aging Chronobiome Study (Acronym-1)
We invite you to participate in a research study where we explore how young and old people differ in their behavioral and biological rhythms. The main criteria to qualify as a research subject are: 1.) you are apparent healthy, 2.) you own a smartphone and 3.) you are either between …
DEVELOPING ORAL LT3 THERAPY FOR HEART FAILURE (DOT3HF)
Parallel, Randomized, Double-Blind, Placebo-Controlled Crossover Clinical Trial The primary objective is to evaluate the safety of oral LT3 in heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF) The secondary objective is to evaluate the feasibility and preliminary efficacy outcomes of oral LT3 therapy …
Analyses of Complement and Other Candidate Fluid Biomarkers in Schizophrenia Spectrum Disorders
The purpose of this research study is to identify biological markers for schizophrenia and related mental illnesses. We are gathering medical information, behavioral assessments, cells and genetic material (DNA), as well as blood and cerebrospinal fluid (CSF), and brain images from persons who appear to have a psychiatric disorder and …
Mixed Meal Tolerance Test and Cirrhosis Study
This is a study of 12 subjects with cirrhosis. Blood is collected at CHPS for metabolomic analysis and MMTT. The meal consumed for MMTT will be a convenience-style breakfast. In addition to research testing on blood, urine, and stool, dietary recalls and the Penn Diet Survey will be conducted. The …
University of Pennsylvania Centralized Observational Research Repository on Neurodegenerative Disease
The aim of this study is to create a repository of both cross-sectional and longitudinal data, imaging and biological specimens for neurodegenerative disease research.
Comparative Effectiveness of Spironolactone Versus Doxycycline for Acne
The goal of this trial is to compare the effectiveness, safety and tolerability of spironolactone and doxycycline hyclate in the treatment of moderate to severe acne in women. Both medications are common treatments for acne, but it is not known how well they compare to one another. Spironolactone was originally …
A Randomized Double-blind Multicenter Placebo-controlled Study to Evaluate the Efficacy Safety and Tolerability of Esketamine Nasal Spray Administered as Monotherapy in Adult Participants with Treatment-resistant Depression
this study is to evaluate the efficacy of each individual dose of esketamine nasal spray, 56 mg and 84 mg, compared with placebo nasal spray in improving depressive symptoms in participants with TRD, as assessed by the change from baseline in the Montgomery-Asberg Depression Rating Scale (MADRS) total score from …
Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer
Surgery is the best treatment for patients with Stage I or II lung cancer; however, nearly 60% of patients have recurrence. Additional immunotherapeutic agents given before surgery may be greatly reduce recurrence. This is a Standard Phase I, 3+3 dose escalation trial designed to evaluate the safety and toxicity of …
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