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Found 70 Lung Disease trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 80 years
All genders
The purpose of this study is to determine if the INOpulse® delivery system, that includes the INOpulse® device, inhaled nitric oxide study drug as delivered via triple lumen nasal cannula can help treat patients with fibrotic interstitial lung disease (fILD) who are on oxygen therapy and who are at risk …
99 years or below
All genders
Phase 1
This research study is being done to study a new way to possibly treat cystic fibrosis lung disease. The investigational drug to be tested in the present study is known by its code name MRT5005. MRT5005 consists of very small particles containing messenger ribonucleic acid (mRNA), which has the genetic …
 A randomized  double-blind  placebo-controlled clinical trial of once-daily inhaled molgramostim nebulizer solution in adult subjects with autoimmune pulmonary alveolar proteinosis (aPAP)
18 years - 99 years
All genders
Phase 3
The present confirmatory phase 3 trial will be conducted to further investigate the efficacy and safety of molgramostim in subjects with aPAP. Investigating how molgramostim improves lung pathology, pathophysiology, and health status in subjects with aPAP in a dose- frequency dependent fashion.
 Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis (RheSolve)
35 years - 99 years
All genders
Interventional
Prospective, randomized, parallel group, double-blind, concurrently controlled, multi-center clinical trial following patients to 2 years to assess the safety and effectiveness the treatment of the symptoms of chronic bronchitis in adult COPD patients with moderate to severe chronic bronchitis.
 Functional Lung Avoidance Radiation Therapy Using Hyperpolarized Xenon-129 MRI
18 years - 99 years
All genders
Phase 1
The primary outcomes will be to establish the safety and feasibility of inhaled imaging in patients with NSCLCand to develop a robust RT planning protocol incorporating both standard of care metrics and those derived from inhaled imaging
 Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)  A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
99 years or below
All genders
Phase 3
The purpose of this study is to find if adding the study drug, nivolumab (also known as OPVIDO), will limit lung cancer from growing back in patients with early stage non-small cell lung cancer. Nivolumab is a drug that may turn on the body's immune system to attack any cancer …
 S1900B A Phase II Study of LOXO-292 in Patients with RET Fusion-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)
18 years - 99 years
All genders
Phase 2
This phase II LUNG-MAP treatment trial studies how well selpercatinib works in treating patients with RET fusion-positive non-small cell lung cancer that is stage IV or has come back (recurrent). Selpercatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth
 Utility of Parametric Response Mapping In Allograft Monitoring After Lung Transplant
18 years - 99 years
All genders
The purpose is to investigate whether parametric response mapping measurements in healthy lung allografts can be used for early detection, prognostication, and phenotyping of CLAD. The target population is bilateral lung transplant recipients who are 6 months post-transplant or later and CLAD free at any of the study institutions. At …
99 years or below
All genders
Lung transplant recipients have the highest risk of readmission after the index admission among solid organ transplant patients. We hypothesize that targeted, individualized rehabilitation plans will reduce the risk of unplanned readmission in the first year after lung transplantation.To address this hypothesis, we will conduct a prospective cohort study of …
 Assessment of Chronic Lung Allograft Dysfunction Using Single-Breath & Multi-Breath Hyperpolarized Xenon 129 MRI
18 years - 90 years
All genders
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 (HP 129-Xe) magnetic resonance imaging (MRI) in diagnosing and predicting the clinical course of patients who received lung transplantation.