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Found 71 Lung Disease trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

50 years - 99 years
All genders
Interventional
The purpose of this study is to collect blood samples to determine if a blood-based test can be used to identify lung cancers that may or may not also be seen on images of lungs. Additionally, the study aims to see if a blood-based test can identify other types of …
18 years - 99 years
All genders
The DECAMP 1 PLUS study will expand on previous early detection studies (DECAMP 1 and 2) to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules. This study will investigate molecular, clinical and imaging features that may distinguish benign versus malignant disease among smokers with indeterminate …
 Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer
99 years or below
All genders
Phase 1
Surgery is the best treatment for patients with Stage I or II lung cancer; however, nearly 60% of patients have recurrence. Additional immunotherapeutic agents given before surgery may be greatly reduce recurrence. This is a Standard Phase I, 3+3 dose escalation trial designed to evaluate the safety and toxicity of …
99 years or below
All genders
Lung transplant recipients have the highest risk of readmission after the index admission among solid organ transplant patients. We hypothesize that targeted, individualized rehabilitation plans will reduce the risk of unplanned readmission in the first year after lung transplantation.To address this hypothesis, we will conduct a prospective cohort study of …
 Assessment of Chronic Lung Allograft Dysfunction Using Single-Breath & Multi-Breath Hyperpolarized Xenon 129 MRI
18 years - 90 years
All genders
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 (HP 129-Xe) magnetic resonance imaging (MRI) in diagnosing and predicting the clinical course of patients who received lung transplantation. 
 Transbronchial Biopsy Assisted by Robot Guidance in the Evaluation of Tumors of the Lung (TARGET)
21 years - 99 years
All genders
Observational
This study is designed to evaluate clinical safety and diagnostic accuracy of the robotic-assisted bronchoscopy with biopsy performed with the Monarch™ Endoscopy Platform in a broad range of patients with pulmonary lesions.
 Study Evaluating the Safety and Efficacy of Itacitinib in Participants With Bronchiolitis Obliterans Syndrome Following Lung Transplantation
99 years or below
All genders
Phase 1
Normal 0 false false false EN-US X-NONE X-NONE You are being invited to participate in a research study because you have Bronchiolitis Obliterans Syndrome. Bronchiolitis Obliterans Syndrome (BOS) is a long term (chronic) rejection process that can occur in the transplanted lungs.  Itacitinib works by blocking your body from producing …
99 years or below
All genders
Phase 2
The main purpose of this study is to examine the efficacy of adding itacitinib (also known as INCB039110) to pembrolizumab in patients with previously untreated metastatic non-small cell lung cancer.
99 years or below
All genders
Phase 1
This is an investigator-initiated, open label phase Ib study examining 2nd line atezolizumab and tocilizumab in a cohort of recurrent/metastatic non-small cell lung cancer patients who have received prior immune checkpoint inhibitor therapy with or without other forms of therapy (i.e. chemotherapy, radiation). Patients with driver mutations in EGFR, ALK, …
 A Study to Investigate the Safety and Efficacy of OTL38 Injection for Intraoperative Imaging of Folate Receptor Positive Lung Nodules
18 years - 99 years
All genders
Observational
A study for persons with suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary nodules within the operating theater, and to …