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Found 40 Heart Failure trials

A listing of Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 99 years
All genders
The research study is being conducted to determine the safety and effectiveness of an investigational device, the Edwards PASCAL Transcatheter Valve Repair System (hereinafter referred to as the PASCAL System), with optimal medical therapy (OMT) compared to optimal medical therapy alone in the treatment of patients with symptomatic, severe tricuspid …
18 years - 99 years
All genders
Interventional
The goal of this study is to determine the safety and performance of the Edwards EVOQUE System in patients who experience at least moderate tricuspid regurgitation and signs of, or symptoms from or prior heart failure hospitalizations for tricuspid regurgitation.
 Studying symptomatic Transthyretin Amyloid Cardiomyopathy for those who Completed the Phase 3 ATTRibute-CM Trial (AG10-301)
18 years - 99 years
All genders
Phase 3
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
 EMPACT-MI
65 years - 99 years
All genders
Phase 3
This clinical trial is enrolling participants that have had a heart attack, (also called acute myocardial infarction or MI). Even though treatments have made progress, researchers are still trying to improve care for heart attack patients, who are at increased risk for heart failure and death. The purpose of this …
18 years - 99 years
All genders
Interventional
The purpose of this research study is to compare the performance of the investigational (experimental) tricuspid valve repair system plus optimal drug therapy with optimal drug therapy alone. Participants will be randomly assigned to treatment with either the TriClip device (device group) or No TriClip device (control group). Participants will …
 A Randomized, Multicenter Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects with Pulmonary Arterial Hypertension, “Ambition” Trial
18 years - 75 years
All genders
Phase 3
Interventional
This clinical research study involves an experimental combination of two drugs, ambrisentan and tadalafil for the treatment of Pulmonary Arterial Hypertension (a narrowing of the arteries connecting the lungs to the heart that leads to an increase in blood pressure). This is also known as PAH. These drugs have been …
 Observation of blood pressure and blood flow in your brain (Hemodynamics)for Patients with Left Ventricular Assist Device
18 years - 99 years
All genders
Observational
The research is being conducted to study the relationship between blood pressure and blood flow in your brain. By making these measurements before and after implantation of your left ventricular assist device (LVAD), this study will help understand how the LVAD affects blood flow to your brain.
 Efficacy of DE-MRI-Guided Fibrosis Ablation vs. Conventional Catheter Ablation of Atrial Fibrillation: The DECAAF II Study
18 years - 60 years
All genders
Observational
You are being asked to participate in this study because you have atrial fibrillation and are planning to undergo an ablation procedure to treat this heart rhythm irregularity.
18 years - 99 years
All genders
Observational
An observational study that aims to collect data over time on the effect of surgery on patient's with a complex fistulizing condition such as: • complex perianal fistula with Crohn’s Disease (CPF-CD) • rectovaginal fistula with Crohn’s Disease (CD-RVF), or • complex cryptoglandular fistulas (CCF). The study will follow patients …
18 years or above
All genders
Observational
This study will be a retrospective chart review of patients who have been diagnosed with benign or malignant pancreatic disease under the practice of Dr. Rohan Jeyarajah, M.D., Dr. Houssam Osman M.D., and Dr. Edward Cho M.D., Sc.M. at Methodist Health System Hospital in Richardson, TX. The Investigators plan to …
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