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Found 40 Heart Failure trials

A listing of Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years or below
All genders
Phase 3
PURPOSE: The overall purpose of the study is to assess the procedural safety profile and clinical efficacy outcomes of an imaging substrate-aided ventricular tachycardia (VT) ablation strategy that avoids general anesthesia, limits inductions, and reduces time devoted to substrate mapping in heart failure patients with severe left ventricular dysfunction. Primary …
99 years or below
All genders
Veno-arterial (VA) extra-corporeal membrane oxygenation (ECMO) is indicated as a haemodynamic rescue strategy in decompensated acute or chronic heart failure presenting as cardiogenic shock. VA ECMO has a number of effects on the circulation including (i) perfusing end-organs, (ii) ventricular unloading, and (iii) improved coronary perfusion. It is a bridge …
 NONCOMPACT- International Consortium for Multimodality Phenotyping in Adults with Non-compaction
18 years - 99 years
All genders
This is a prospective, multicenter observational study to identify clinical, genetic and imaging predictors of clinical outcome in patients with suspected non-compaction cardiomyopathy Many healthy people have increased trabeculations without consequences, however, some may develop blood clots, heart rhythm disorders or heart failure later in life. Currently we cannot predict …
 Comparative Effectiveness of Spironolactone Versus Doxycycline for Acne
16 years - 40 years
Female
Phase 4
The goal of this trial is to compare the effectiveness, safety and tolerability of spironolactone and doxycycline hyclate in the treatment of moderate to severe acne in women. Both medications are common treatments for acne, but it is not known how well they compare to one another. Spironolactone was originally …
99 years or below
All genders
Observational study of adults with congestive heart failure and normal healthy participants using Magnetic Resonance Imaging (MRI) to compare changes in the lymphatic system (thin tubes and lymph nodes that run throughout the body).
99 years or below
All genders
Parallel, Randomized, Double-Blind, Placebo-Controlled Crossover Clinical Trial The primary objective is to evaluate the safety of oral LT3 in heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF) The secondary objective is to evaluate the feasibility and preliminary efficacy outcomes of oral LT3 therapy …
 Implantation of the HeartMate 3 in Subjects with Heart Failure
18 years - 99 years
All genders
This is a prospective, post-market, multi-center, non-blinded, single arm study of the HeartMate 3 Left Ventricular Assist System (LVAS). The objective of this study is to evaluate the implantation of the HM3.
18 years - 99 years
All genders
The primary purpose of this study is to test whether the dapagliflozin (Dapa) will improve exercise duration in people with Heart Failure (HF). In HF, patients are limited in their ability to do all the things they want to do, and exercise as much as they would like, due to …
 JK07 in Subjects with Heart Failure with Reduced Ejection Fraction (HFrEF)
18 years - 80 years
All genders
Phase 1
Patients with Heart Failure with Reduced Ejection Fraction (HFrEF) will be invited to participate in this study. HFrEF is a condition in which the heart pumps a lower than normal amount of blood. The purpose of this study is to evaluate the safety and activity of the investigational product in …
 Dapagliflozin Effect on symptoms and blomarkers in patients with Heart Failure (DEFINE-HF)
18 years - 100 years
All genders
Interventional
The purpose of this study is to find out if a drug called dapagliflozin would be effective in improving the blood tests and symptoms related to your heart failure.
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