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Found 43 HIV Infections trials

A listing of HIV Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Long-Term Follow-up of Older HIV-infected Adults in the ACTG: Addressing Issues of Aging  HIV Infection and Inflammation
40 years - 99 years
All genders
Interventional
This study will look at the relationships between HIV infection, age and the immune system, and how these relate to the development of non-infectious illnesses such as heart disease, kidney disease, cancer, memory problems, and diabetes. Further, we will look at how demographic factors, behaviors, and social factors like social …
18 years - 99 years
All genders
Phase 1
The purpose of this study is to test the safety of SAR441236, a study drug that has not been tested in humans before now. The study will also look at how long SAR441236 stays in the body after one dose and after four doses. It will also look at whether …
18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this study is to see if an investigational vaccine for cytomegalovirus (CMV), called Triplex®, is safe when given to people with both Human Immunodeficiency Virus (HIV) and CMV.
18 years - 99 years
All genders
Interventional
The purpose of this study is to study how well patients that receive a kidney from an HIV+ organ donor do over 10 years compared to patients that receive a kidney from an HIV- donor. People 18 years of age and older with end-stage renal disease and HIV, and who …
18 years - 99 years
All genders
Phase 1
Interventional
The research study is being conducted to test an experimental drug, GS-8588, for the treatment and remission of human immunodeficiency virus (HIV) infection. GS-8588 is a special type of protein, called an antibody, that helps the immune system bring your immune cells closer to the cells infected with HIV. Finding …
 Evaluation of in vivo Neuroinflammation Using 18F-NOS (PET/CT) in HIV Positive and Negative Subjects with Opioid Use Disorder and Healthy Controls
18 years - 60 years
All genders
Phase 1
Study Purpose: The goal of this study is to learn more about how opiate use and HIV affects inflammation in the brain. We will study this using a type of Positron Emission Tomography (PET/CT) scan using a radioactive imaging drug called 18F-NOS that can be used to measure inflammation in …
 Size and Decay of HIV-1 Reservoirs in Tissues and Cerebrospinal Fluid in Participants on Long-Term Antiretroviral Therapy
18 years - 99 years
All genders
The purpose of this study is to look at where human immunodeficiency virus (HIV) might be “hiding” when standard lab tests show that HIV levels in the blood are very low.
 UPCC 06717 / AMC 101: A Pilot Study of Ibrutinib and R-da-EPOCH for Front Line Treatment of AIDS-Related Lymphomas
18 years - 64 years
All genders
Phase 1
Non-Hodgkin lymphoma  is a potentially curable condition with standard cancer treatment drugs (chemotherapy) and steroids. Standard lymphoma treatment includes chemotherapy, or cancer-fighting drugs, called etoposide, vincristine, cyclophosphamide, prednisone and doxorubicin (called EPOCH).  
 A5369: HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) as Therapeutic Vaccination in HIV-Infected Persons with Viral Suppression on Antiretroviral Therapy
99 years or below
All genders
Phase 1
A5369 is a phase I/IIa, randomized, double-blind, placebo-controlled study to evaluate the safety, immunogenicity, and efficacy of p24CE/full-length Gag DNA, as a therapeutic vaccine in HIV-1 infected persons. The study targets to enroll 40 participants. All participants are well-suppressed on ART, current CD4 T cell counts greater than 500 cells/mm3, …
 Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1
18 years - 99 years
All genders
Phase 2
Interventional
This study will assess the safety, tolerability, pharmacokinetics, and antiviral activity of long-acting cabotegravir (CAB LA) plus the broadly neutralizing monoclonal antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), in adults living with HIV-1 with suppressed plasma viremia.
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