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Found 44 HIV Infections trials

A listing of HIV Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Study to Evaluate the Safety and Efficacy of GS-5423 and GS-2872 in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection

Study to Evaluate the Safety and Efficacy of GS-5423 and GS-2872 in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection

18 years - 65 years
All genders
Phase 1
Interventional
The primary objective of this study is to evaluate the safety and tolerability of a combination of the broadly neutralizing antibodies (bNAbs) GS-5423 and GS-2872 in combination with the HIV capsid inhibitor lenacapavir (LEN).

Neuropsychiatric sequalae of COVID-19

18 years - 65 years
All genders
The purpose of this study is to explore possible neurological complications resulting from prior COVID-19 infection. Neurological symptoms, including ‘brain fog’, depression, and/or anxiety can be disabling. This study aims to determine the prevalence and severity of these symptoms. Unfortunately, little is known about these neuropsychiatric symptoms, particularly in patients …
 Neural and Motor Functional Changes in HIV and Stroke Before and After Robot-Assisted Neurorehabilitation

Neural and Motor Functional Changes in HIV and Stroke Before and After Robot-Assisted Neurorehabilitation

18 years - 100 years
All genders
The purpose of this research study is twofold: to study the role HIV has on the brain’s function and more particularly, the relationship between HIV and stroke; and to study how the presence of HIV effects robot-assisted rehabilitation after stroke, and its association with clinical improvement.
 Towards Objective Metrics to Quantify the Role of HIV and Increasing Cognitive Demand on Instrumental ADLs in People Aging with HIV

Towards Objective Metrics to Quantify the Role of HIV and Increasing Cognitive Demand on Instrumental ADLs in People Aging with HIV

50 years - 100 years
All genders
The objective of this proposal is to examine the utility of a robot-based approach to study instrumental activities of daily living (IADLs) function and cognitive-motor performance in persons aging with HIV. IADLs often require high levels of executive functioning during the performance of motor activities, but there are no good …

The OHART Study

18 years - 99 years
All genders
The purpose of this study is to investigate different oral and systemic problems including dental carries, periodontal disease, dry mouth, high cholesterol, diabetes, heart disease, and osteoporosis, observed in patients living with HIV on antiretroviral therapy. 

Evaluating the Efficacy and Safety of Long-Acting Lenacapavir for HIV PrEP

16 years - 100 years
Male
Phase 3
The primary objective of the PURPOSE2 study is to evaluate the efficacy of lenacapavir (LEN) in preventing the risk of contracting human immunodeficiency virus (HIV). The study will be conducted in 2 parts: a cross-sectional study (Incidence Phase) and a double-blind, randomized study (Randomized Phase).1) The Incidence Phase will include …

HIV Prevention Research Division Generic Pre-screen protocol

18 years - 45 years
All genders
The purpose of this study is to determine if you may be eligible to participate in one of ourcurrent research studies being conducted at the University of Pennsylvania. The purposes ofthese studies are to test different methods that might protect people against viruses thatcause transmittable infections or to develop better …

Evaluating an Investigative Drug Letermovir (Prevymis) in Adults with Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV)

40 years - 99 years
All genders
Interventional
The purpose of this study is to test letermovir when given to people who have both well-controlled HIV infection and asymptomatic CMV infection. This study will also gather data on the effectiveness of letermovir to reduce inflammation when compared to no anti-CMV study treatment. In addition, the study will collect …

HOPE in Action Prospective Multicenter Clinical Trial of HIV+ Deceased Donor Kidney Transplants for HIV+ Recipients

All genders
Use of an HIV+ deceased donor could increase the risk of death, transplant-related or HIV-related complications; alternatively with effective antiretroviral treatment and careful HIV+ donor selection, these risks may be comparable to kidney transplant using an HIV-negative donor. We hypothesize that receiving a kidney transplant from an HIV+ donor will …
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