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Found 55 transplant trials

A listing of transplant medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 CD24Fc for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005) (CATHY)
18 years - 99 years
All genders
Phase 3
Interventional
The study compares two acute graft-versus-host disease (aGVHD) prophylaxis regimens: CD24Fc/tacrolimus / methotrexate (CD24Fc/Tac/MTX) versus placebo/tacrolimus / methotrexate (placebo/Tac/MTX) in the setting of myeloablative conditioning (MAC), matched unrelated donor (MUD) allogeneic hematopoietic stem cell transplantation in participants with acute leukemia (AML/ALL) or myelodysplastic syndrome (MDS).
 Assessment of Chronic Lung Allograft Dysfunction Using Single-Breath & Multi-Breath Hyperpolarized Xenon 129 MRI
18 years - 90 years
All genders
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 (HP 129-Xe) magnetic resonance imaging (MRI) in diagnosing and predicting the clinical course of patients who received lung transplantation. 
18 years - 99 years
All genders
Phase 3
Pleae refer to Section 3 (Objectives and Endpoints) of the full protocol Please refer to Section 3.1 (Primary Endpoint) of the full protocol Please refer to Section 3.2 (Secondary Endpoints) of the full protocol
99 years or below
All genders
A study to evaluate posoleucel (ALVR105); an allogeneic, off-the-shelf multi-virus specific T cell therapy that targets six viral pathogens: BK virus, cytomegalovirus, adenovirus, Epstein-Barr virus, human herpesvirus 6 and JC virus. We would like to rely on WCG as the IRB of record for this study.
99 years or below
All genders
Use of an HIV+ deceased donor could increase the risk of death, transplant-related or HIV-related complications; alternatively with effective antiretroviral treatment and careful HIV+ donor selection, these risks may be comparable to kidney transplant using an HIV-negative donor. We hypothesize that receiving a kidney transplant from an HIV+ donor will …
 EVALUATION OF PATIENT OUTCOMES FROM THE KIDNEY ALLOGRAFT OUTCOMES ALLOSURE REGISTRY (KOAR)
99 years or below
All genders
This is a multicenter, non-blinded, prospective observational cohort study of 1000 patients enrolled in an AlloSure testing registry, including 300 patients at centers with planned renal surveillance biopsies at 12 months post-transplantation. The other 700 patients will be from centers that do not perform protocol surveillance biopsies. This registry study …
 Sample Collection for Prospera Enhancement
18 years - 99 years
All genders
Interventional
The research study is being conducted to learn how well a test called Prospera can detect rejection in a transplanted kidney after a biopsy. If results of the biopsy do not indicate rejection, the study team will follow your condition by reviewing your clinical visits for one year, at which …
99 years or below
All genders
The purpose of this study is to look at the effectiveness of an investigational test called the Aptima CMV Quantification Diagnostic Assay (Aptima CMV Quant Assay) to measure levels of CMV in plasma. The target population is subjects who have tested positive for cytomegalovirus (CMV) after receiving a solid-organ transplant …