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Found 55 neurology trials

A listing of neurology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Spironolactone for Regulating Blood Pressure after Intracerebral Hemorrhage
18 years - 99 years
All genders
Blood pressure treatment is important for all survivors of intracerebral hemorrhage (ICH). High blood pressure after ICH puts patients at high risk for future strokes and memory problems. Nearly all doctors agree that patients  who have had a brain hemorrhage should be treated with blood pressure medications. But doctors are …
 MG0004: A randomized  open-label extension study to investigate the long-term safety  tolerability  and efficacy of rozanolixizumab in adult patients with generalized myasthenia gravis
99 years or below
All genders
Phase 3
Rozanolixizumab is a humanized IgG4 monoclonal antibody that is being developed as an inhibitor of the activity of the neonatal Fc receptor (FcRn) for IgG. By blocking the activity of neonatal FcRn, rozanolixizumab accelerates the catabolism of antibodies and reduces the serum IgG concentration, including pathogenic IgG in MG patients, …
 CILT + HD-tDCS as a Potential Treatment for Primary Progressive Aphasia
45 years - 80 years
All genders
Phase 2
Primary Progressive Aphasia, or PPA, is a neurodegenerative disease that affects language abilities. A person with PPA may have difficulties speaking, understanding speech, reading, or writing, and these difficulties worsen over time.The purpose of this study is to determine whether a form of non-invasive brain stimulation called High-definition Transcranial Direct …
 To identify reliable markers of LRRK2 activity in human CSF.
30 years - 99 years
Accepts healthy volunteer
All genders
The purpose of this research study is to evaluate new tests for Parkinson's disease (PD) that may help in developing better treatments.
 Evaluate a Next Generation Portable Diagnostic Platform for Determination of Emergency Large Vessel Stroke
22 years - 99 years
All genders
Phase 2
Observational
The purpose of this study is to collect robust cerebral blood flow velocity (CBFV) data collected by transcranial Doppler ultrasound (TCD) to validate the Occlusion Index (OI) as a diagnostic algorithm tool to aid in clinical decision making for large vessel occlusion
 Using Behavioral Economics to Improve Mobility for Adults with Stroke
18 years - 99 years
All genders
Observational
The overall objective of this study is to evaluate the feasibility of a connected health mobility intervention for community-dwelling adults with stroke. We will examine the outcomes of an 8 week mobility intervention on steps per day. Additionally, we will explore individual phenotypes as they relate to intervention responsiveness, which …
 For persons with drug-resistant focal onset seizures, a type of Epilepsy, the study of of cvl-865 as adjunctive therapy.
18 years - 99 years
All genders
Phase 2
Interventional
Trial of CVL-865 as Adjunctive Therapy in Adults With Drug-Resistant Focal Onset Seizures
 Trial-Ready Cohort for the Prevention of Alzheimer's Dementia
50 years - 85 years
All genders
Observational
The purpose of this study is to develop a large, biomarker-confirmed, trial-ready cohort to facilitate rapid enrollment into AD prevention trials. Will utilize feeder registries as well as participants with known biomarker status. Enrollment into TRC involves in-clinic evaluation and biomarker confirmation, with additional visits every 6 months. This may …
 A Study of TAK-071 in People With Parkinson Disease
40 years - 85 years
All genders
Phase 2
Interventional
It is hoped that TAK-071 will help people with Parkinson's disease to walk with better balance. The main aim of the study is to check if there is a difference in how participants walk after treatment with TAK-071. Another aim is to see if it improves how participants think and …
 HELIOS- A:A Study to Evaluate the Efficacy and Safety of ALN-TTRSC02 in Patients with Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)
18 years - 85 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the efficacy and safety of vutrisiran (ALN-TTRSC02) in patients with hereditary transthyretin amyloidosis (hATTR amyloidosis). Participants will receive vutrisiran or the reference comparator patisiran during the Treatment Period.