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Found 18 genetics trials

A listing of genetics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Does Apolipoprotein A-V (APOA5) the genetic code of a protein, affect the levels of triglycerides (a type of fat) in the blood,
18 years - 99 years
All genders
The purpose of this study is to determine how changes in the genetic code of a protein called Apolipoprotein A-V (APOA5) may affect the levels of triglycerides (a type of fat) in the blood, and the risk of heart disease and acute pancreatitis. People who have these changes, as well …
 Study to determine safety and tolerability of oral lucerastat in adult subjects with Fabry disease
18 years - 99 years
All genders
Phase 3
The purpose of this study is to study how a new investigational drug called lucerastat works in research subjects. Taking part in a research study is different from getting regular medical care. The aim of regular care is to improve your health. The aim of a research study is to …
 A Phase 2b Study to Assess the Efficacy  Safety  and Tolerability of Vupanorsen (PF-07285557) in Statin-Treated Participants with Dyslipidemia
40 years - 99 years
All genders
Phase 2
Phase 2b, double-blind, placebo-controlled, parallel group study to provide data on efficacy, safety, tolerability and PK of vupanorsen administered subcutaneously at various doses and regimens with patients with dyslipidemia. Patients will participate for approximately 10 months, and will have blood draws, physical exams, ECGs, and MRIs.
 PATH Study: Pomalidomide for the Treatment of Bleeding in Hereditary Hemorrhagic Telangiectasia
18 years - 99 years
All genders
This research study is to determine the safety and tolerability of pomalidomide for the treatment of HHT; to determine if pomalidomide treatment improves quality of life in HHT; to determine whether a continued response to pomalidomide is evident 12 weeks after treatment discontinuation; to develop a biorepository for future studies …
 Undiagnosed Diseases Network- Clinical and Genetic Evaluation of Patients with Undiagnosed  Disorders
18 years - 99 years
All genders
We are doing this research study to improve diagnosis and care for people with undiagnosed diseases. We are asking you to take part in this research study because you have an undiagnosed disease. About 8000 people will take part over the entire course of this research study. The NIH is …
 Defining the role of germline genetic variants in gastric cancer tumorigenesis
99 years or below
All genders
The research study is being conducted to better understand factors that lead to gastric (stomach) cancer, including differences in our genes that may put some people at increased risk of developing gastric cancer compared to other people. Both people with increased risk as well as people with average risk of …
99 years or below
All genders
Phase 1
Multi-center, open-label, first in human (FIH) Phase 1 study of the safety, tolerability, feasibility, and preliminary efficacy of the administration of genetically modified autologous T cells (CART-TnMUC1 cells) engineered to express a chimeric antigen receptor (CAR) capable of recognizing the tumor antigen, TnMUC1 and activating the T cell (CARTTnMUC1 cells). …
 Robotic Nipple Sparing Mastectomy (NSM) Study
18 years - 80 years
Female
Phase 3
The goal of this prospective study is to evaluate the safety and effectiveness of the da Vinci Xi Surgical System, instruments, and accessories in Nipple Sparing Mastectomy, otherwise known as NSM procedures.
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