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Found 18 genetics trials

A listing of genetics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Genetics of Alcohol Dependence and Withdrawal in African Americans
18 years - 100 years
All genders
The purpose of this study is to learn things that will help us better understand alcohol dependence, other kinds of substance dependence, and aspects of personality and behavior in African Americans. DNA, the material that carries genetic instructions, will be taken from blood, and used to study genes for these …
 The Gen-Y Study: Randomized trial of universal vs. guideline-directed germline testing among young adults with cancer
18 years - 40 years
All genders
Our study aims to determine whether genetic testing should be recommended for young adults with cancer. This type of testing can show if your cancer may be caused by inherited risk.  This information can help guide effective screening and treatment for cancer in young adults and their families. This is …
 Assessing the Impact of Lipoprotein (a) Lowering With TQJ230 on Major Cardiovascular Events in Patients With CVD (Lp(a)HORIZON)
18 years - 80 years
All genders
Phase 3
This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)
 DCPMS: Dialated Cardiomyopathy Precision Medicine Study
1 years - 100 years
All genders
This study aims to understand the effects of potential familial/genetic links in an otherwise unclear origin of a patient's heart disease.
 Understanding the Genetics of Central Centrifugal Cicatricial Alopecia
99 years or below
All genders
The purpose of this study is to characterize gene mutations associated Central Centrifugal Cicatricial Alopecia (CCCA). The Penn Medicine BioBank (PMBB) supports researchers by providing centralized access to a large number of annotated blood and tissue samples. Clinician identified patients with CCCA and appropriate controls will be recruited from the …
99 years or below
All genders
Subjects with unusual lipids in subjects with known or suspected genetic variants that may be associated with change in lipoprotein kinetics will have two-night, one-day inpatient stay in CHPS, during which they will undergo extensive evaluation of lipoprotein kinetics using stable isotope techniques, OFTT, and OGTT. Subjects will complete a …
 NONCOMPACT- International Consortium for Multimodality Phenotyping in Adults with Non-compaction
18 years - 99 years
All genders
This is a prospective, multicenter observational study to identify clinical, genetic and imaging predictors of clinical outcome in patients with suspected non-compaction cardiomyopathy Many healthy people have increased trabeculations without consequences, however, some may develop blood clots, heart rhythm disorders or heart failure later in life. Currently we cannot predict …
 Study to determine safety and tolerability of oral lucerastat in adult subjects with Fabry disease
18 years - 99 years
All genders
Phase 3
The purpose of this study is to study how a new investigational drug called lucerastat works in research subjects. Taking part in a research study is different from getting regular medical care. The aim of regular care is to improve your health. The aim of a research study is to …
 Defining the role of germline genetic variants in gastric cancer tumorigenesis
99 years or below
All genders
The research study is being conducted to better understand factors that lead to gastric (stomach) cancer, including differences in our genes that may put some people at increased risk of developing gastric cancer compared to other people. Both people with increased risk as well as people with average risk of …
99 years or below
All genders
Phase 1
Multi-center, open-label, first in human (FIH) Phase 1 study of the safety, tolerability, feasibility, and preliminary efficacy of the administration of genetically modified autologous T cells (CART-TnMUC1 cells) engineered to express a chimeric antigen receptor (CAR) capable of recognizing the tumor antigen, TnMUC1 and activating the T cell (CARTTnMUC1 cells). …
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